SCHEMBL32668569

SCHEMBL32668569

O=C(c1ccc(Oc2ncccn2)cc1)N1CCC(O)(Cn2cnc3c(cnn3-c3ccc(F)c(CO)c3)c2=O)CC1

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 20/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17870005 1.00 USP7 (0.54) USP7
SCHEMBL32668412 0.93 USP7 (0.56) USP7
SCHEMBL17869513 0.93 USP7 (0.56) USP7
SCHEMBL17868934 0.90 USP7 (0.63) USP7
SCHEMBL17869801 0.89 USP7 (0.64) USP7
SCHEMBL30967230 0.89 USP7 (0.64) USP7
SCHEMBL32668506 0.89 USP7 (0.54) USP7
SCHEMBL17894665 0.89 USP7 (0.54) USP7
SCHEMBL17868984 0.89 USP7 (0.58) USP7
SCHEMBL17869105 0.87 USP7 (0.57) USP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3623372-B1 PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS VALO HEALTH INC (US) 2026-02-04 EP claimed
EP-3623372-B1 PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS VALO HEALTH INC (US) 2026-02-04 EP disclosed