SCHEMBL32669211

SCHEMBL32669211

C(=N/Nc1nc(NCc2ccccn2)nc(N2CCOCC2)n1)\c1c[nH]c2ccccc12

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 12/20 0.70
▸ KMT2A Q03164 8/20 0.70
▸ MEN1 O00255 7/20 0.70
▸ GAA P10253 6/20 0.70
▸ LMNA P02545 4/20 0.70
▸ CYP1A2 P05177 1/20 0.70
▸ CYP3A4 P08684 1/20 0.70
▸ CYP2C9 P11712 1/20 0.70
▸ CYP2C19 P33261 1/20 0.70
▸ PIKFYVE Q9Y2I7 1/20 0.70
▸ ALDH1A1 P00352 4/20 0.66
▸ NPSR1 Q6W5P4 3/20 0.66
▸ THRB P10828 2/20 0.66
▸ L3MBTL1 Q9Y468 3/20 0.61
▸ POLB P06746 2/20 0.61
▸ TDP1 Q9NUW8 2/20 0.48
▸ ATM Q13315 1/20 0.48
▸ RECQL P46063 1/20 0.47
▸ MAPK1 P28482 1/20 0.47
▸ NLRP3 Q96P20 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32669196 0.93 MAPT (0.67) MAPTKMT2AMEN1GAALMNA
SCHEMBL3325959 0.86 MAPT (0.62) MAPTKMT2AMEN1GAALMNA
SCHEMBL10195928 0.86 MAPT (0.62) MAPTKMT2AMEN1GAALMNA
SCHEMBL3088439 0.86 MAPT (0.62) MAPTKMT2AMEN1GAALMNA
SCHEMBL16844670 0.84 MAPT (0.71) MAPTKMT2AMEN1GAALMNA
SCHEMBL32669369 0.83 MAPT (0.58) MAPTKMT2AMEN1GAALMNA
SCHEMBL23345483 0.80 MAPT (0.79) MAPTKMT2AMEN1GAALMNA
SCHEMBL10198706 0.80 MAPT (0.70) MAPTKMT2AMEN1GAALMNA
SCHEMBL423662 0.80 MAPT (0.70) MAPTKMT2AMEN1GAALMNA
SCHEMBL423663 0.80 MAPT (0.70) MAPTKMT2AMEN1GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260034141-A1 METHODS AND COMPOSITIONS FOR TREATING MALIGNANT CANCERS 6J BIOTECHNOLOGY HONG KONG LTD (HK) 2026-02-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034141-A1 METHODS AND COMPOSITIONS FOR TREATING MALIGNANT CANCERS MCL1, GLI1, BECN1 MAPT 538/4885KMT2A 2267/4885MEN1 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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