SCHEMBL32671069

SCHEMBL32671069

CCc1cc2c(Br)ccnc2n1S(=O)(=O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PIK3C3 Q8NEB9 1/20 0.46
PTGDR2 Q9Y5Y4 9/20 0.45
SRC P12931 2/20 0.39
CYP2C19 P33261 1/20 0.36
RECQL P46063 1/20 0.36
MTNR1B P49286 1/20 0.35
CCKAR P32238 1/20 0.35
TSHR P16473 1/20 0.35
HTR6 P50406 2/20 0.35
SLC40A1 Q9NP59 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15645284 1.00 PIK3C3 (0.46) PIK3C3PTGDR2SRCCYP2C19RECQL
SCHEMBL13505075 0.88 PTGDR2 (0.43) PIK3C3PTGDR2SRCCYP2C19RECQL
SCHEMBL3413866 0.88 PTGDR2 (0.45) PIK3C3PTGDR2SRCCYP2C19RECQL
SCHEMBL20839913 0.88 PTGDR2 (0.42) PIK3C3PTGDR2SRCCYP2C19RECQL
SCHEMBL20839615 0.88 PTGDR2 (0.42) PIK3C3PTGDR2SRCCYP2C19RECQL
SCHEMBL4309127 0.87 PTGDR2 (0.42) PIK3C3PTGDR2SRCCYP2C19RECQL
SCHEMBL15644621 0.86 PTGDR2 (0.41) PIK3C3PTGDR2SRCCYP2C19RECQL
SCHEMBL18980291 0.85 PIK3C3 (0.46) PIK3C3PTGDR2SRCCYP2C19RECQL
SCHEMBL3417907 0.85 PTGDR2 (0.41) PIK3C3PTGDR2SRCCYP2C19RECQL
SCHEMBL30135049 0.84 PTGDR2 (0.48) PIK3C3PTGDR2SRCCYP2C19CCKAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078119-A1 DEGRADER COMPOUNDS AND USES THEREOF BRISTOL MYERS SQUIBB CO (US) 2026-03-19 US disclosed
EP-4688771-A1 NOVEL FAK DEGRADER COMPOUNDS AND USES THEREOF Bristol-Myers Squibb Company (US) 2026-02-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078119-A1 DEGRADER COMPOUNDS AND USES THEREOF CTTN, SRC, PTK2 PIK3C3 1915/4885PTGDR2 1918/4885SRC 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.