Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23882660 | 1.00 | MAOB (0.50) | MAOBMAOATHRATHRBBRD4 | |
| SCHEMBL23905914 | 0.88 | MAOB (0.47) | MAOBMAOATHRATHRBBRD4 | |
| SCHEMBL23906278 | 0.86 | BRD4 (0.54) | MAOBMAOATHRATHRBBRD4 | |
| SCHEMBL23905844 | 0.81 | CYP19A1 (0.63) | MAOBMAOABRD4CREBBPGRM5 | |
| SCHEMBL30251254 | 0.79 | CYP3A4 (0.65) | MAOBTHRATHRBHPGDSMN1; SMN2 | |
| SCHEMBL23882776 | 0.79 | CYP3A4 (0.65) | MAOBTHRATHRBHPGDSMN1; SMN2 | |
| SCHEMBL23906288 | 0.78 | BRD4 (0.53) | MAOBMAOABRD4CREBBPGRM5 | |
| SCHEMBL23905149 | 0.78 | MAOB (0.77) | MAOBMAOABRD4CREBBPGRM5 | |
| SCHEMBL23882676 | 0.76 | MAOB (0.62) | MAOBMAOATHRATHRBGRM5 | |
| SCHEMBL30251352 | 0.76 | MAOB (0.62) | MAOBMAOATHRATHRBGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126835-B1 | INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR | JANSSEN PHARMACEUTICA NV (BE) | 2026-02-18 | — | — | EP | claimed |