SCHEMBL32675801

SCHEMBL32675801

CCCCc1nc2c(N)nnc(OC(C)C)c2n1Cc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.61
TLR8 Q9NR97 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30663254 0.99 TLR7 (0.60) TLR7TLR8
SCHEMBL29840784 0.91 TLR7 (0.59) TLR7TLR8
SCHEMBL29109915 0.91 TLR7 (0.59) TLR7TLR8
SCHEMBL29109822 0.90 TLR7 (0.60) TLR7TLR8
SCHEMBL29840931 0.89 TLR7 (0.62) TLR7TLR8
SCHEMBL29840923 0.89 TLR7 (0.61) TLR7TLR8
SCHEMBL31395470 0.88 TLR7 (0.49) TLR7TLR8
SCHEMBL29840844 0.88 TLR7 (0.61) TLR7TLR8
SCHEMBL29840960 0.88 TLR7 (0.61) TLR7TLR8
SCHEMBL29109804 0.87 TLR7 (0.52) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4288438-B1 DERIVATIVES OF IMIDAZO[4,5-D]PYRIDAZINE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION SANOFI SA (FR) 2026-02-18 EP claimed