SCHEMBL32676378

SCHEMBL32676378

O=C(N[C@@H](Cc1nc2ccccc2o1)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.66

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 3/20 0.52
▸ TP53 P04637 3/20 0.52
▸ SLC17A5 Q9NRA2 1/20 0.48
▸ MDM2 Q00987 6/20 0.45
▸ CASP3 P42574 2/20 0.45
▸ TNF P01375 1/20 0.42
▸ TLR2 O60603 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20526762 1.00 MDM4 (0.52) MDM4TP53SLC17A5MDM2CASP3
SCHEMBL20526765 1.00 MDM4 (0.52) MDM4TP53SLC17A5MDM2CASP3
SCHEMBL20526778 0.89 MDM2 (0.49) MDM4TP53SLC17A5MDM2CASP3
SCHEMBL20526634 0.89 MDM4 (0.47) MDM4TP53SLC17A5MDM2CASP3
SCHEMBL20526635 0.89 MDM4 (0.47) MDM4TP53SLC17A5MDM2CASP3
SCHEMBL20526770 0.89 MDM4 (0.47) MDM4TP53SLC17A5MDM2CASP3
SCHEMBL20526767 0.89 MDM4 (0.47) MDM4TP53SLC17A5MDM2CASP3
SCHEMBL20526779 0.89 MDM2 (0.49) MDM4TP53SLC17A5MDM2CASP3
SCHEMBL20526746 0.87 MDM4 (0.46) MDM4TP53SLC17A5MDM2CASP3
SCHEMBL20526625 0.87 MDM2 (0.51) MDM4TP53SLC17A5MDM2CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260049101-A1 TOPICAL TREATMENT OF SKIN CANCER USING OLIGOPEPTIDES BACOBA AG (CH) 2026-02-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049101-A1 TOPICAL TREATMENT OF SKIN CANCER USING OLIGOPEPTIDES NGLY1, MC1R, EGFR MDM4 2280/4885TP53 190/4885SLC17A5 2654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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