Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 13/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16497986 | 0.87 | CACNA1B (0.61) | CACNA1BPOLBCNR1LMNASMN1; SMN2 | |
| SCHEMBL16497704 | 0.87 | CACNA1B (0.61) | CACNA1BPOLBCNR1LMNASMN1; SMN2 | |
| SCHEMBL16497855 | 0.87 | CACNA1B (0.61) | CACNA1BPOLBCNR1LMNASMN1; SMN2 | |
| SCHEMBL65629 | 0.86 | CACNA1B (0.58) | CACNA1BPOLBKMT2ALMNASMN1; SMN2 | |
| SCHEMBL66782 | 0.86 | CACNA1B (0.58) | CACNA1BPOLBKMT2ALMNASMN1; SMN2 | |
| SCHEMBL65628 | 0.86 | CACNA1B (0.58) | CACNA1BPOLBKMT2ALMNASMN1; SMN2 | |
| SCHEMBL66781 | 0.86 | CACNA1B (0.58) | CACNA1BPOLBKMT2ALMNASMN1; SMN2 | |
| SCHEMBL2422335 | 0.85 | CACNA1B (0.60) | CACNA1BPOLBCNR1LMNASMN1; SMN2 | |
| SCHEMBL2844339 | 0.85 | CACNA1B (0.60) | CACNA1BPOLBCNR1LMNASMN1; SMN2 | |
| SCHEMBL66012 | 0.84 | CACNA1B (0.57) | CACNA1BPOLBKMT2ACNR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010062927-A2 | NOVEL SUBSTITUTED OCTAHYDROCYCLOPENTA(C)PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS | ABBOTT LABORATORIES (US) | 2010-06-03 | — | — | WO | disclosed |