SCHEMBL32677355

SCHEMBL32677355

CCOC(=O)N1CCN(Cc2ccc(Nc3ncc(F)c(-c4ccc5nc(N(CC)CC)sc5c4)n3)nc2)CC1

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DYRK2 Q92630 16/20 0.70
CDK6 Q00534 4/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26447987 1.00 DYRK2 (0.70) DYRK2CDK6
SCHEMBL31672937 0.94 DYRK2 (0.67) DYRK2CDK6
SCHEMBL26447964 0.94 DYRK2 (0.67) DYRK2CDK6
SCHEMBL32677358 0.93 DYRK2 (0.82) DYRK2CDK6
SCHEMBL26447973 0.93 DYRK2 (0.82) DYRK2CDK6
SCHEMBL26447972 0.89 DYRK2 (0.79) DYRK2CDK6
SCHEMBL26451835 0.88 DYRK2 (0.71) DYRK2CDK6
SCHEMBL30569710 0.86 DYRK2 (0.74) DYRK2CDK6
SCHEMBL26451650 0.86 DYRK2 (0.74) DYRK2CDK6
SCHEMBL30679278 0.86 DYRK2 (0.73) DYRK2CDK6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559485-B2 CDK6/DYRK2 dual-target inhibitor, and preparation method therefor and use thereof JIANGSU TASLY DIYI PHARMACEUTICAL CO. , LTD. (CN) 2026-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559485-B2 CDK6/DYRK2 dual-target inhibitor, and preparation method therefor and use thereof CDK6, CDK2, CDKL1 DYRK2 23/4885CDK6 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.