SCHEMBL32678201

SCHEMBL32678201

O=C(CNC(=O)c1ccc2[nH]cc(-c3cccc(N4CCOCC4)c3)c2c1)NCCc1c[nH]c2ccc(F)cc12

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SNCA P37840 9/20 0.60
GSK3B P49841 3/20 0.54
TRPV1 Q8NER1 1/20 0.45
SPR P35270 1/20 0.45
NOTUM Q6P988 2/20 0.44
MTNR1A P48039 1/20 0.44
MTNR1B P49286 1/20 0.44
CDK4 P11802 2/20 0.43
CCND1 P24385 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
SIRT1 Q96EB6 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32678203 1.00 SNCA (0.60) SNCAGSK3BTRPV1SPRNOTUM
SCHEMBL32678204 0.93 SNCA (0.59) SNCAGSK3BTRPV1SPRNOTUM
SCHEMBL32678202 0.93 SNCA (0.59) SNCAGSK3BTRPV1SPRNOTUM
SCHEMBL32678205 0.87 GSK3B (0.65) SNCAGSK3BTRPV1SPRNOTUM
SCHEMBL32678365 0.86 GSK3B (0.59) SNCAGSK3BTRPV1SPRNOTUM
SCHEMBL32678367 0.86 GSK3B (0.59) SNCAGSK3BTRPV1SPRNOTUM
SCHEMBL32678229 0.84 GSK3B (0.71) SNCAGSK3BTRPV1SPRNOTUM
SCHEMBL32678230 0.84 GSK3B (0.71) SNCAGSK3BTRPV1SPRNOTUM
SCHEMBL32678268 0.82 GSK3B (0.68) SNCAGSK3BTRPV1SPRNOTUM
SCHEMBL32678272 0.82 GSK3B (0.68) SNCAGSK3BTRPV1SPRNOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025264058-A9 NOVEL COMPOUND AND USE THEREOF 주식회사 진큐어 2026-02-26 WO claimed
WO-2025264058-A9 NOVEL COMPOUND AND USE THEREOF 주식회사 진큐어 2026-02-26 WO disclosed