SCHEMBL32678293

SCHEMBL32678293

O=C(NCCc1c[nH]c2ccccc12)c1ccnc(-c2ccc3[nH]cc(-c4ccccc4)c3c2)c1

nearest known ligand 0.67

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 7/20 0.67
CCND1 P24385 7/20 0.67
GSK3B P49841 6/20 0.64
MEN1 O00255 3/20 0.62
KMT2A Q03164 3/20 0.62
NPC1 O15118 1/20 0.62
RAB9A P51151 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.56
NAMPT P43490 1/20 0.53
SIRT1 Q96EB6 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32678226 0.94 CDK4 (0.65) CDK4CCND1GSK3BMEN1KMT2A
SCHEMBL32678223 0.94 CDK4 (0.65) CDK4CCND1GSK3BMEN1KMT2A
SCHEMBL32678349 0.92 CDK4 (0.56) CDK4CCND1GSK3BMEN1KMT2A
SCHEMBL32678348 0.92 CDK4 (0.56) CDK4CCND1GSK3BMEN1KMT2A
SCHEMBL32678250 0.91 CDK4 (0.55) CDK4CCND1GSK3BMEN1KMT2A
SCHEMBL32678254 0.91 CDK4 (0.55) CDK4CCND1GSK3BMEN1KMT2A
SCHEMBL32678191 0.91 SNCA (0.58) CDK4CCND1GSK3BNAMPTSIRT1
SCHEMBL32678168 0.91 SNCA (0.62)
SCHEMBL32678195 0.91 SNCA (0.58) CDK4CCND1GSK3BNAMPTSIRT1
SCHEMBL32678165 0.91 SNCA (0.62)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025264058-A9 NOVEL COMPOUND AND USE THEREOF 주식회사 진큐어 2026-02-26 WO claimed
WO-2025264058-A9 NOVEL COMPOUND AND USE THEREOF 주식회사 진큐어 2026-02-26 WO disclosed