Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | TEK | Q02763 | 1/20 | 0.55 |
| ▸ | TTBK1 | Q5TCY1 | 7/20 | 0.55 |
| ▸ | TTBK2 | Q6IQ55 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | EGFR | P00533 | 3/20 | 0.50 |
| ▸ | ABL1 | P00519 | 3/20 | 0.50 |
| ▸ | BCR | P11274 | 3/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.50 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.48 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32679379 | 0.87 | KDR (0.54) | KDRTEKTTBK1TTBK2MAPT | |
| SCHEMBL32679402 | 0.82 | TTBK1 (0.47) | KDRTEKTTBK1TTBK2MAPT | |
| SCHEMBL32679394 | 0.82 | EGFR (0.52) | KDRTEKTTBK1TTBK2MAPT | |
| SCHEMBL32679393 | 0.82 | EGFR (0.52) | KDRTEKTTBK1TTBK2MAPT | |
| SCHEMBL32679373 | 0.81 | TTBK1 (0.45) | KDRTEKTTBK1TTBK2MAPT | |
| SCHEMBL32679395 | 0.81 | TTBK1 (0.45) | KDRTEKTTBK1TTBK2MAPT | |
| SCHEMBL4415573 | 0.81 | PIP4K2A (0.47) | KDRTEKTTBK1TTBK2MAPT | |
| SCHEMBL32679397 | 0.80 | TTBK1 (0.44) | KDRTEKTTBK1TTBK2MAPT | |
| SCHEMBL32679398 | 0.80 | PIP4K2A (0.48) | KDRTEKTTBK1TTBK2MAPT | |
| SCHEMBL32679401 | 0.80 | TTBK1 (0.44) | KDRTEKTTBK1TTBK2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120424083-B | Pyrrolo pyrimidine compound and preparation method and application thereof | 江西省肿瘤医院(江西省第二人民医院、江西省癌症中心) | 2026-02-27 | — | — | CN | disclosed |