SCHEMBL32681106

SCHEMBL32681106

COc1ccc(Cl)cc1S(=O)(=O)Nc1noc2cc(Cn3cccn3)ccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ KAT6A Q92794 20/20 1.00
▸ KAT7 O95251 19/20 1.00
▸ KAT6B Q8WYB5 12/20 0.81
▸ KAT5 Q92993 9/20 0.74
▸ KAT8 Q9H7Z6 9/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22817340 1.00 KAT6A (1.00) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL32681091 0.90 KAT6A (1.00) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL22829042 0.90 KAT6A (1.00) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL22817416 0.90 KAT7 (1.00) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL22802411 0.87 KAT6A (0.80) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL32681112 0.85 KAT7 (1.00) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL22817339 0.85 KAT6A (1.00) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL22828486 0.85 KAT7 (1.00) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL22817422 0.85 KAT7 (1.00) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL21596803 0.84 KAT7 (0.78) KAT6AKAT7KAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062406-A1 Benzisoxazole Sulfonamide Derivatives PFIZER (US) 2026-03-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062406-A1 Benzisoxazole Sulfonamide Derivatives KAT8, KAT5, KAT7 KAT6A 7/4885KAT7 3/4885KAT6B 16/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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