Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 20/20 | 0.43 |
| ▸ | CCND1 | P24385 | 20/20 | 0.43 |
| ▸ | CCND3 | P30281 | 20/20 | 0.43 |
| ▸ | CDK6 | Q00534 | 20/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32684080 | 0.94 | CDK4 (0.41) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL32684159 | 0.92 | CDK4 (0.43) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL32684171 | 0.91 | CDK4 (0.39) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL32684071 | 0.89 | CDK4 (0.44) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL32684079 | 0.89 | CDK4 (0.39) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL32684169 | 0.89 | CDK4 (0.42) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL32684115 | 0.88 | CDK4 (0.43) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL32684186 | 0.88 | CDK4 (0.41) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL32684501 | 0.87 | CDK4 (0.41) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL32684313 | 0.84 | CDK4 (0.38) | CDK4CCND1CCND3CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260070915-A1 | SUBSTITUTED 7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINES AS SELECTIVE CDK2/4 INHIBITORS | INCYTE CORP (US) | 2026-03-12 | — | — | US | claimed |
| US-20260070915-A1 | SUBSTITUTED 7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINES AS SELECTIVE CDK2/4 INHIBITORS | INCYTE CORP (US) | 2026-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260070915-A1 | SUBSTITUTED 7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINES AS SELECTIVE CDK2/4 INHIBITORS | CDK4, CDK2, CCNC | CDK4 1/4885CCND1 23/4885CCND3 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.