Sugi Predict

Sugi Predict / Compounds / SCHEMBL32685406

SCHEMBL32685406

SCHEMBL32685406

N=C(N)NCCC[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O

nearest known ligand 0.60

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 17/20 0.60
▸ NPY1R P25929 11/20 0.60
▸ NPY5R Q15761 10/20 0.60
▸ NPY2R P49146 7/20 0.60
▸ TFPI P10646 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29476505 1.00 NPY4R (0.60) NPY4RNPY1RNPY5RNPY2RTFPI
SCHEMBL29476428 1.00 NPY4R (0.60) NPY4RNPY1RNPY5RNPY2RTFPI
SCHEMBL30787055 1.00 NPY4R (0.60) NPY4RNPY1RNPY5RNPY2RTFPI
SCHEMBL30787041 0.96 NPY4R (0.57) NPY4RNPY1RNPY5RNPY2RTFPI
SCHEMBL30787062 0.96 NPY4R (0.57) NPY4RNPY1RNPY5RNPY2RTFPI
SCHEMBL30787048 0.96 NPY4R (0.57) NPY4RNPY1RNPY5RNPY2RTFPI
SCHEMBL30787044 0.96 NPY4R (0.57) NPY4RNPY1RNPY5RNPY2RTFPI
SCHEMBL30787061 0.96 NPY4R (0.57) NPY4RNPY1RNPY5RNPY2RTFPI
SCHEMBL30787054 0.96 NPY4R (0.57) NPY4RNPY1RNPY5RNPY2RTFPI
SCHEMBL30787057 0.96 NPY4R (0.57) NPY4RNPY1RNPY5RNPY2RTFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4711004-A2 METHOD OF TREATING MELANOCORTIN-4 RECEPTOR PATHWAY-ASSOCIATED DISORDERS Rhythm Pharmaceuticals, Inc. (US) 2026-03-18 — — EP disclosed
Send feedback