Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CETP | P11597 | 4/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7631529 | 0.86 | TSHR (0.68) | TSHRCETPFOLH1SRCPDPK1 | |
| SCHEMBL10685051 | 0.84 | PPARD (0.39) | NR1I2ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL9505799 | 0.84 | CETP (0.42) | TSHRCETPFOLH1SRCALDH1A1 | |
| Hydrochloric Acid SCHEMBL7372995 | 0.84 | TSHR (0.66) | TSHRCETPFOLH1SRCPDPK1 | |
| SCHEMBL11409691 | 0.83 | PPARD (0.38) | NR1I2ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL27882401 | 0.83 | TSHR (0.59) | TSHRCETPFOLH1SRCPDPK1 | |
| SCHEMBL27560451 | 0.81 | TSHR (0.58) | TSHRCETPFOLH1SRCMAPT | |
| SCHEMBL27866003 | 0.80 | TSHR (0.56) | TSHRCETPFOLH1SRCMAPT | |
| Propionic Acid SCHEMBL28574297 | 0.80 | CETP (0.62) | TSHRCETPFOLH1SRCPDPK1 | |
| SCHEMBL3266718 | 0.79 | TSHR (0.44) | TSHRCETPSRCPDPK1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0694298-B1 | PREFORMED GLASS IONOMER FILLER WHICH CAN SUSTAINEDLY RELEASE FLUORIDE ION AND DENTAL COMPOSITION CONTAINING THE SAME | SHOFU INC (JP) | 2010-06-09 | — | — | EP | disclosed |
| US-5883153-A | SUSTAINED RELEASE GLASS IONOMERS | SHOFU INC. (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0694298-A1 | PREFORMED GLASS IONOMER FILLER WHICH CAN SUSTAINEDLY RELEASE FLUORIDE ION AND DENTAL COMPOSITION CONTAINING THE SAME | SHOFU INC. (JP) | 1996-01-31 | — | — | EP | disclosed |