Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 17/20 | 0.71 |
| ▸ | MTOR | P42345 | 2/20 | 0.71 |
| ▸ | PIK3CD | O00329 | 13/20 | 0.66 |
| ▸ | PIK3CB | P42338 | 11/20 | 0.66 |
| ▸ | PIK3CG | P48736 | 11/20 | 0.66 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.63 |
| ▸ | PLK4 | O00444 | 1/20 | 0.63 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.63 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.63 |
| ▸ | GAK | O14976 | 1/20 | 0.63 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.63 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.63 |
| ▸ | STK16 | O75716 | 1/20 | 0.63 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.63 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.63 |
| ▸ | NQO2 | P16083 | 1/20 | 0.63 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.63 |
| ▸ | JAK1 | P23458 | 1/20 | 0.63 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.63 |
| ▸ | TYK2 | P29597 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1865013 | 1.00 | PIK3CA (0.71) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL19142705 | 0.93 | PIK3CA (0.70) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL1497518 | 0.90 | PIK3CA (0.75) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL14385291 | 0.89 | PIK3CA (0.65) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL32686054 | 0.89 | PIK3CA (0.73) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL1858455 | 0.89 | PIK3CA (0.73) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL1863624 | 0.89 | PIK3CA (0.73) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL32686146 | 0.89 | PIK3CA (0.71) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL1865580 | 0.89 | PIK3CA (0.71) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL1685822 | 0.88 | PIK3CA (0.72) | PIK3CAMTORPIK3CDPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709480-A1 | 5,6-FUSED BICYCLIC AMIDES AND COMPOSITIONS FOR USE AS 15-PROSTAGLANDIN DEHYDROGENASE MODULATORS | Amgen Inc. (US) | 2026-03-18 | — | — | EP | disclosed |