Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 5/20 | 0.36 |
| ▸ | NOS2 | P35228 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11962828 | 0.80 | KDM4E (0.59) | KDM4EHTTPDE4BKMT2ANPC1 | |
| SCHEMBL125976 | 0.80 | SMPD3 (0.50) | KDM4EHTTKMT2AMAPTNPC1 | |
| Hydrochloric Acid SCHEMBL6805756 | 0.78 | SMPD3 (0.48) | KDM4EHTTKMT2AMAPTNPC1 | |
| SCHEMBL23104339 | 0.77 | KDM4E (0.56) | KDM4EHTTPDE4BKMT2AMAPT | |
| SCHEMBL13153941 | 0.77 | KDM4E (0.56) | KDM4EHTTPDE4BKMT2ASMN1; SMN2 | |
| SCHEMBL30579310 | 0.77 | SMPD3 (0.35) | KDM4EHTTKMT2AMAPTNPC1 | |
| SCHEMBL31548681 | 0.77 | CHEK1 (0.40) | KDM4EHTTPDE4BKMT2AMAPT | |
| SCHEMBL1369575 | 0.77 | KDM4E (0.34) | KDM4EHTTKMT2AMAPTNPC1 | |
| SCHEMBL25495619 | 0.77 | KDM4E (0.34) | KDM4EHTTKMT2AMAPTNPC1 | |
| SCHEMBL6228444 | 0.75 | TYK2 (0.37) | KDM4EHTTKMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4710923-A2 | INDOLE AHR INHIBITORS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |