Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 7/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 5/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.38 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24950007 | 1.00 | BTK (0.43) | BTKKDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL32686700 | 1.00 | BTK (0.43) | BTKKDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL24950000 | 1.00 | BTK (0.43) | BTKKDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL32686524 | 0.91 | BTK (0.48) | BTKKDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL24949946 | 0.91 | BTK (0.48) | BTKKDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL29492883 | 0.85 | BTK (0.46) | BTKKDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL30578524 | 0.85 | BTK (0.46) | BTKKDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL23301590 | 0.84 | BTK (0.45) | BTKKDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL24950192 | 0.84 | BTK (0.45) | BTKKDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL24950101 | 0.84 | BTK (0.45) | BTKKDM1AMAOBKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4051677-B1 | BICYCLIC NITROGEN CONTAINING HETEROCYCLES AS INHIBITORS OF SALT-INDUCED KINASE SIK2 | CANCER RESEARCH TECH LTD (GB) | 2026-03-18 | — | — | EP | disclosed |