SCHEMBL32686983

SCHEMBL32686983

CCO[C@@H]1[C@@H](O)CN[C@@H]1Cc1ccc(-c2ccnnc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ CYP2D6 P10635 3/20 0.44
▸ SMN1; SMN2 Q16637 3/20 0.44
▸ LMNA P02545 1/20 0.44
▸ MAPK1 P28482 1/20 0.44
▸ HIF1A Q16665 1/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ ALDH1A1 P00352 1/20 0.44
▸ CYP2C9 P11712 1/20 0.44
▸ CYP2C19 P33261 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ SLC2A1 P11166 1/20 0.44
▸ WNT3A P56704 2/20 0.32
▸ BCHE P06276 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32687679 0.86 CYP2D6 (0.40) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL32687147 0.86 CYP2D6 (0.40) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL32687276 0.85 CYP2D6 (0.42) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL32687709 0.84 CYP2D6 (0.44) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL32687489 0.82 CYP2D6 (0.42) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL32687256 0.80 CYP2D6 (0.35) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL32687247 0.78 CYP2D6 (0.39) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL32687727 0.78 CYP2D6 (0.39) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL32687507 0.78 ERCC1 (0.40) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL32687279 0.78 CYP2D6 (0.39) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-04-23 — — US disclosed
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, MCL1 CYP2D6 3364/4885SMN1; SMN2 958/4885LMNA 2918/4885
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS KRAS, MYC, NRAS CYP2D6 2744/4885SMN1; SMN2 1323/4885LMNA 2258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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