SCHEMBL32687754

SCHEMBL32687754

NC(=O)CCO[C@@H]1[C@@H](O)CN[C@@H]1Cc1ccc(-c2cnn(C(F)F)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CYP2D6 P10635 3/20 0.38
▸ SMN1; SMN2 Q16637 3/20 0.38
▸ LMNA P02545 1/20 0.38
▸ MAPK1 P28482 1/20 0.38
▸ HIF1A Q16665 1/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38
▸ CYP2C19 P33261 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ SLC2A1 P11166 1/20 0.38
▸ BRD4 O60885 2/20 0.33
▸ CREBBP Q92793 2/20 0.33
▸ GRM2 Q14416 7/20 0.32
▸ BCHE P06276 1/20 0.30
▸ ROCK2 O75116 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32687247 0.86 CYP2D6 (0.39) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL32687752 0.84 CYP2D6 (0.36) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL32687615 0.81 CYP2D6 (0.32) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL32687328 0.81 CYP2D6 (0.37) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL32687373 0.77 CYP2D6 (0.39) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL32687784 0.76 CYP2D6 (0.41) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL31421019 0.75 CYP2D6 (0.37) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL32687525 0.73 CYP2D6 (0.37) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL32687489 0.72 CYP2D6 (0.42) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL32687162 0.70 CYP2D6 (0.46) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-04-23 — — US disclosed
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, MCL1 CYP2D6 3364/4885SMN1; SMN2 958/4885LMNA 2918/4885
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS KRAS, MYC, NRAS CYP2D6 2744/4885SMN1; SMN2 1323/4885LMNA 2258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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