Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3268141 | 0.86 | ADORA2A (0.69) | ADORA2AADORA1 | |
| SCHEMBL3269211 | 0.83 | ADORA2A (0.61) | ADORA2AADORA1 | |
| SCHEMBL3274098 | 0.81 | ADORA2A (0.59) | ADORA2AADORA1 | |
| SCHEMBL3274150 | 0.78 | ADORA2A (0.68) | ADORA2AADORA1 | |
| SCHEMBL3272200 | 0.78 | ADORA2A (0.80) | ADORA2AADORA1 | |
| SCHEMBL3273415 | 0.76 | ADORA2A (0.78) | ADORA2AADORA1 | |
| SCHEMBL3269399 | 0.76 | ADORA2A (1.00) | ADORA2AADORA1 | |
| SCHEMBL3272518 | 0.75 | ADORA2A (0.64) | ADORA2AADORA1 | |
| SCHEMBL3274417 | 0.74 | ADORA2A (0.71) | ADORA2AADORA1 | |
| SCHEMBL3268454 | 0.74 | ADORA2A (1.00) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349857-B1 | PURINE DERIVATIVES AS PURINERGIC RECEPTOR ANTAGONISTS | VERNALIS RES LTD (GB) | 2010-06-16 | — | — | EP | disclosed |
| US-7452894-B2 | Purine derivatives as purinergic receptor antagonists | VERNALIS RESEARCH LIMITED (GB) | 2008-11-18 | — | — | US | disclosed |
| US-7452894-B2 | Purine derivatives as purinergic receptor antagonists | VERNALIS RESEARCH LIMITED (GB) | 2008-11-18 | — | — | US | disclosed |
| US-7452894-B2 | Purine derivatives as purinergic receptor antagonists | VERNALIS RESEARCH LIMITED (GB) | 2008-11-18 | — | — | US | disclosed |