Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.59 |
| ▸ | ALK | Q9UM73 | 10/20 | 0.54 |
| ▸ | MET | P08581 | 3/20 | 0.54 |
| ▸ | CDK7 | P50613 | 2/20 | 0.53 |
| ▸ | CDK9 | P50750 | 1/20 | 0.53 |
| ▸ | INSR | P06213 | 3/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.49 |
| ▸ | AXL | P30530 | 2/20 | 0.49 |
| ▸ | NEK2 | P51955 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.48 |
| ▸ | PLK4 | O00444 | 1/20 | 0.48 |
| ▸ | STK25 | O00506 | 1/20 | 0.48 |
| ▸ | RIOK3 | O14730 | 1/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | CASK | O14936 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | GAK | O14976 | 1/20 | 0.48 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31251214 | 0.90 | EGFR (0.61) | EGFRALKMETCDK7CDK9 | |
| SCHEMBL32690395 | 0.83 | CDK7 (0.53) | EGFRALKMETCDK7CDK9 | |
| SCHEMBL31251194 | 0.83 | CDK7 (0.53) | EGFRALKMETCDK7CDK9 | |
| SCHEMBL31251235 | 0.81 | ALK (0.54) | EGFRALKMETCDK7CDK9 | |
| SCHEMBL31251139 | 0.80 | CDK7 (0.53) | EGFRALKMETCDK7CDK9 | |
| SCHEMBL31251379 | 0.80 | CDK7 (0.52) | ALKMETCDK7CDK9INSR | |
| SCHEMBL25002639 | 0.79 | ALK (0.55) | EGFRALKMETCDK7CDK9 | |
| SCHEMBL13394913 | 0.79 | ALK (0.74) | EGFRALKMETCDK7INSR | |
| SCHEMBL31251238 | 0.79 | ALK (0.55) | ALKMETCDK7CDK9PTK2 | |
| SCHEMBL31251128 | 0.79 | CDK7 (0.54) | ALKMETCDK7CDK9PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260085050-A1 | TRIPLE KINASE INHIBITORS | UNOGEN BIOTECH LTD (US) | 2026-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260085050-A1 | TRIPLE KINASE INHIBITORS | ALK, ERBB2, ERBB3 | EGFR 4/4885ALK 1/4885MET 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.