Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14429599 | 0.91 | ADORA2A (0.61) | ADORA2AADORA1 | |
| SCHEMBL3269836 | 0.90 | ADORA2A (0.58) | ADORA2AADORA1 | |
| SCHEMBL5467614 | 0.89 | ADORA2A (0.75) | ADORA2AADORA1 | |
| SCHEMBL3267585 | 0.86 | ADORA2A (0.66) | ADORA2AADORA1 | |
| SCHEMBL14429605 | 0.86 | ADORA2A (0.63) | ADORA2AADORA1 | |
| SCHEMBL3267851 | 0.85 | ADORA2A (0.82) | ADORA2AADORA1 | |
| SCHEMBL3268042 | 0.82 | ADORA2A (0.59) | ADORA2AADORA1 | |
| SCHEMBL3273511 | 0.82 | ADORA2A (0.59) | ADORA2AADORA1 | |
| SCHEMBL5461300 | 0.81 | ADORA2A (0.56) | ADORA2AADORA1 | |
| SCHEMBL14429601 | 0.78 | ADORA2A (0.65) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349857-B1 | PURINE DERIVATIVES AS PURINERGIC RECEPTOR ANTAGONISTS | VERNALIS RES LTD (GB) | 2010-06-16 | — | — | EP | disclosed |
| US-7452894-B2 | Purine derivatives as purinergic receptor antagonists | VERNALIS RESEARCH LIMITED (GB) | 2008-11-18 | — | — | US | disclosed |
| US-7452894-B2 | Purine derivatives as purinergic receptor antagonists | VERNALIS RESEARCH LIMITED (GB) | 2008-11-18 | — | — | US | disclosed |
| US-7452894-B2 | Purine derivatives as purinergic receptor antagonists | VERNALIS RESEARCH LIMITED (GB) | 2008-11-18 | — | — | US | disclosed |