Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11238090 | 0.89 | TDP1 (0.50) | PLAUTDP1GPR35TSHRALDH1A1 | |
| SCHEMBL30135431 | 0.83 | PLAU (0.59) | PLAUCYP3A4TDP1GPR35TSHR | |
| SCHEMBL187375 | 0.83 | PLAU (0.59) | PLAUCYP3A4TDP1GPR35TSHR | |
| SCHEMBL28049512 | 0.82 | TSHR (0.50) | PLAUCYP3A4TDP1GPR35TSHR | |
| SCHEMBL10974014 | 0.81 | PLAU (0.45) | PLAUCYP3A4TDP1GPR35TSHR | |
| SCHEMBL3395115 | 0.81 | PLAU (0.45) | PLAUCYP3A4TDP1GPR35TSHR | |
| SCHEMBL27466789 | 0.81 | PLAU (0.45) | PLAUCYP3A4TDP1GPR35TSHR | |
| SCHEMBL28922681 | 0.81 | TDP1 (0.42) | PLAUTDP1GPR35TSHRALDH1A1 | |
| SCHEMBL3837781 | 0.81 | CYP3A4 (0.63) | PLAUCYP3A4TDP1GPR35TSHR | |
| SCHEMBL3842417 | 0.81 | TSHR (0.55) | PLAUCYP3A4TDP1GPR35TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2591034-A1 | RIGID POLYURETHANE FOAM | BASF SE (DE) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004229-A1 | RIGID POLYURETHANE FOAM | BASF SE (DE) | 2012-01-12 | — | — | WO | disclosed |
| US-4814359-A | POLYETHERURETHANE FOAM | UNION CARBIDE CORPORATION (US) | 1989-03-21 | — | — | US | disclosed |
| US-4052500-A | HEATING IN AIR | AMERICAN CYANAMID COMPANY (US) | 1977-10-04 | — | — | US | disclosed |
| US-4052501-A | ADHESION IMPROVERS | AMERICAN CYANAMID COMPANY (US) | 1977-10-04 | — | — | US | disclosed |