Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7048351 | 0.87 | PTPN1 (0.51) | TRPV1PTPN1PTGS1PDE4ASNCA | |
| SCHEMBL7077134 | 0.87 | PTPN1 (0.51) | TRPV1PTPN1PTGS1PDE4ASNCA | |
| SCHEMBL2138794 | 0.83 | PTPN1 (0.50) | TRPV1PTPN1PTGS1PDE4ASNCA | |
| SCHEMBL14283790 | 0.81 | PTGS1 (0.43) | PTPN1PTGS1PDE4ASNCAPDE3A | |
| SCHEMBL7143550 | 0.81 | PTPN1 (0.52) | TRPV1PTPN1PTGS1PDE4ASNCA | |
| SCHEMBL7080800 | 0.81 | TRPV1 (0.48) | TRPV1PTPN1PTGS1PDE4ASNCA | |
| SCHEMBL2166287 | 0.77 | PTGS1 (0.45) | TRPV1PTPN1PTGS1PDE4ASNCA | |
| SCHEMBL16435130 | 0.77 | PTPN1 (0.51) | TRPV1PTPN1PTGS1PDE4ASNCA | |
| SCHEMBL9356354 | 0.77 | PTPN1 (0.51) | TRPV1PTPN1PTGS1PDE4ASNCA | |
| SCHEMBL9356348 | 0.77 | PTPN1 (0.51) | TRPV1PTPN1PTGS1PDE4ASNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2573188-A2 | Process for the production of fine chemicals | Metanomics GmbH (DE) | 2013-03-27 | — | — | EP | disclosed |
| EP-2194140-A2 | Process for the production of fine chemicals | Metanomics GmbH (DE) | 2010-06-09 | — | — | EP | disclosed |