SCHEMBL3273932

SCHEMBL3273932

C=CC(=O)OC(C)C(OC)OC

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.42
HPGD P15428 1/20 0.32
ALDH1A1 P00352 4/20 0.31
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
CYP3A4 P08684 1/20 0.31
HSD17B10 Q99714 1/20 0.31
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propene SCHEMBL19056916 0.90 TSHR (0.38) TSHR
Ethylene Glycol SCHEMBL57562 0.87 TSHR (0.40) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL26841662 0.84 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL12791661 0.83 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9862506 0.81 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1284885 0.79 TSHR (0.46) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL8965914 0.79 TSHR (0.46) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL23142579 0.79 TSHR (0.36) TSHR
SCHEMBL1374266 0.77 TSHR (0.45) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL10758374 0.77 TSHR (0.45) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1680546-B1 TEMPORARY WET STRENGTH ADDITIVES PROCTER & GAMBLE (US) 2009-04-08 EP claimed
US-20070251657-A1 Temporary wet strength additives BARCUS ROBERT L 2007-11-01 US claimed
US-7258763-B2 Temporary wet strength additives THE PROCTER + GAMBLE COMPANY (US) 2007-08-21 US claimed
US-7217339-B2 Fibrous structures exhibiting improved wet strength properties THE PROCTER & GAMBLE COMPANY (US) 2007-05-15 US claimed
US-7125469-B2 Temporary wet strength resins THE PROCTER & GAMBLE COMPANY (US) 2006-10-24 US claimed
EP-1680546-A2 TEMPORARY WET STRENGTH ADDITIVES THE PROCTER & GAMBLE COMPANY (US) 2006-07-19 EP claimed
WO-2005038132-A2 TEMPORARY WET STRENGTH ADDITIVES THE PROCTER & GAMBLE COMPANY (US) 2005-04-28 WO claimed
US-20050082024-A1 Temporary wet strength additives THE PROCTER & GAMBLE COMPANY 2005-04-21 US claimed
US-6197919-B1 ADDITION POLYMERIZATION OF ANIONIC AND CATIONIC MONOMERS; CHAIN TRANSFER HERCULES INCORPORATED 2001-03-06 US claimed
EP-0915918-A1 RESINS OF AMPHOTERIC ALDEHYDE POLYMERS AND USE OF SAID RESINS AS TEMPORARY WET-STRENGTH OR DRY-STRENGTH RESINS FOR PAPER HERCULES INCORPORATED (US) 1999-05-19 EP claimed
WO-1998054237-A1 RESINS OF AMPHOTERIC ALDEHYDE POLYMERS AND USE OF SAID RESINS AS TEMPORARY WET-STRENGTH OR DRY-STRENGTH RESINS FOR PAPER HERCULES INCORPORATED (US) 1998-12-03 WO claimed
US-5138002-A Temporary wet strength resins with nitrogen heterocyclic nonnucleophilic functionalities and paper products containing same THE PROCTER & GAMBLE COMPANY (US) 1992-08-11 US claimed
US-7691233-B2 Temporary wet strength additives THE PROCTER & GAMBLE COMPANY (US) 2010-04-06 US disclosed
US-20070251657-A1 Temporary wet strength additives BARCUS ROBERT L 2007-11-01 US disclosed
US-7258763-B2 Temporary wet strength additives THE PROCTER + GAMBLE COMPANY (US) 2007-08-21 US disclosed
US-20050082024-A1 Temporary wet strength additives THE PROCTER & GAMBLE COMPANY 2005-04-21 US disclosed
US-5138002-A Temporary wet strength resins with nitrogen heterocyclic nonnucleophilic functionalities and paper products containing same THE PROCTER & GAMBLE COMPANY (US) 1992-08-11 US disclosed
US-5085736-A Temporary wet strength resins and paper products containing same THE PROCTER & GAMBLE COMPANY (US) 1992-02-04 US disclosed
US-4981557-A Temporary wet strength resins with nitrogen heterocyclic nonnucleophilic functionalities and paper products containing same THE PROCTER & GAMBLE COMPANY (US) 1991-01-01 US disclosed
EP-0350276-A2 Temporary wet strength resins with nitrogen heterocyclic nonnucleophilic functionalities and paper products containing same THE PROCTER & GAMBLE COMPANY (US) 1990-01-10 EP disclosed