Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 0.58 |
| ▸ | PTPRB | P23467 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | SCP2 | P22307 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alanine SCHEMBL3282143 | 1.00 | PTPRA (0.58) | PTPRAPTPRBMEN1KMT2ARAB9A | |
| Alanine SCHEMBL3281125 | 1.00 | PTPRA (0.58) | PTPRAPTPRBMEN1KMT2ARAB9A | |
| Alanine SCHEMBL3274213 | 0.95 | PTPRA (0.56) | PTPRAPTPRBMEN1KMT2ARAB9A | |
| Leucine SCHEMBL3275050 | 0.90 | PTPRA (0.60) | PTPRAPTPRBMEN1KMT2ARAB9A | |
| SCHEMBL3275224 | 0.89 | KMT2A (0.62) | PTPRAPTPRBMEN1KMT2ARAB9A | |
| SCHEMBL3275812 | 0.81 | MEN1 (0.41) | PTPRAPTPRBMEN1KMT2ARAB9A | |
| SCHEMBL3275818 | 0.81 | MEN1 (0.53) | PTPRAPTPRBMEN1KMT2ARAB9A | |
| Acetic Acid SCHEMBL313911 | 0.80 | KMT2A (0.45) | PTPRAPTPRBMEN1KMT2ARAB9A | |
| SCHEMBL15087108 | 0.80 | PTPRA (0.84) | PTPRAPTPRBMEN1KMT2ARAB9A | |
| SCHEMBL13338326 | 0.77 | LCK (0.52) | MEN1KMT2ARAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7695930-B2 | Method for the detection, identification and/or quantification of microoganisms with peptidase activity using phenoxazinone derivatives as enzyme substrates | BIOMERIEUX (FR) | 2010-04-13 | — | — | US | disclosed |
| US-20080286820-A1 | Novel phenoxazinone derivatives as enzyme substrates and use thereof as indicator in the detection of microorganisms with peptidase activity | BIOMERIEUX (FR) | 2008-11-20 | — | — | US | disclosed |
| US-7420054-B2 | Phenoxazinone derivatives as enzyme substrates and use thereof as indicator in the detection of microorganisms with peptidase activity | BIOMERIEUX (FR) | 2008-09-02 | — | — | US | disclosed |
| US-20060121551-A1 | Novel phenoxazinone derivatives as enzyme substrates and use thereof as indicator in the detection of microorganisms with peptidase activity | BIOMERIEUX (FR) | 2006-06-08 | — | — | US | disclosed |
| EP-1625117-A1 | NOVEL PHENOXAZINONE DERIVATIVES AS ENZYME SUBSTRATES AND USE THEREOF AS INDICTOR IN THE DETECTION OF MICROORGANISMS WITH PEPTIDASE ACTIVITY | BIOMERIEUX (FR) | 2006-02-15 | — | — | EP | disclosed |
| WO-2004101536-A1 | NOVEL PHENOXAZINONE DERIVATIVES AS ENZYME SUBSTRATES AND USE THEREOF AS INDICTOR IN THE DETECTION OF MICROORGANISMS WITH PEPTIDASE ACTIVITY | BIOMERIEUX (FR) | 2004-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060121551-A1 | Novel phenoxazinone derivatives as enzyme substrates and use thereof as indicator in the detection of microorganisms with peptidase activity | PEPD, CTRL, PM20D2 | PTPRA 1042/4885PTPRB 628/4885MEN1 2241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.