Sugi Predict

Sugi Predict / Compounds / SCHEMBL3275585

SCHEMBL3275585

SCHEMBL3275585

CCOc1cccc(C(=CCSc2ccc(OCC(=O)O)c(I)c2)c2ccccc2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PPARD Q03181 7/20 0.52
▸ PPARA Q07869 1/20 0.41
▸ FFAR1 O14842 3/20 0.40
▸ L3MBTL1 Q9Y468 2/20 0.40
▸ GLA P06280 1/20 0.40
▸ ALDH1A1 P00352 2/20 0.39
▸ MAPK1 P28482 2/20 0.39
▸ LMNA P02545 1/20 0.39
▸ MTNR1A P48039 2/20 0.39
▸ MTNR1B P49286 2/20 0.39
▸ HPGD P15428 1/20 0.39
▸ KLK7 P49862 1/20 0.39
▸ KLK14 Q9P0G3 1/20 0.39
▸ ST14 Q9Y5Y6 1/20 0.39
▸ MEN1 O00255 1/20 0.38
▸ TSHR P16473 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ NPC1 O15118 2/20 0.37
▸ RAB9A P51151 2/20 0.37
▸ KAT6A Q92794 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3269445 1.00 PPARD (0.52) PPARDPPARAFFAR1L3MBTL1GLA
SCHEMBL3271616 0.98 PPARD (0.52) PPARDPPARAFFAR1L3MBTL1GLA
SCHEMBL3276127 0.92 PPARD (0.57) PPARDPPARAFFAR1L3MBTL1GLA
SCHEMBL3269875 0.92 PPARD (0.57) PPARDPPARAFFAR1L3MBTL1GLA
SCHEMBL3270677 0.91 PPARD (0.53) PPARDPPARAFFAR1L3MBTL1ALDH1A1
SCHEMBL3270846 0.91 PPARD (0.53) PPARDPPARAFFAR1L3MBTL1ALDH1A1
SCHEMBL3270869 0.89 PPARD (0.67) PPARDPPARA
SCHEMBL3271150 0.89 PPARD (0.67) PPARDPPARA
SCHEMBL3270089 0.89 PPARD (0.53) PPARDPPARAFFAR1L3MBTL1MAPK1
SCHEMBL3269463 0.89 PPARD (0.60) PPARDPPARAFFAR1L3MBTL1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1558572-B1 NOVEL COMPOUNDS AND THEIR USE AS PRAR-MODULATORS HIGH POINT PHARMACEUTICALS LLC (US) 2010-06-30 — — EP claimed
US-7129268-B2 Peroxisome proliferator activated receptor-active arylene acetic acid derivatives NOVO NORDISK A/S (DK) 2006-10-31 — — US claimed
US-20050070583-A1 Novel compounds, their preparation and use VTVX HOLDINGS II LLC 2005-03-31 — — US claimed
EP-1558572-B1 NOVEL COMPOUNDS AND THEIR USE AS PRAR-MODULATORS HIGH POINT PHARMACEUTICALS LLC (US) 2010-06-30 — — EP disclosed
US-7129268-B2 Peroxisome proliferator activated receptor-active arylene acetic acid derivatives NOVO NORDISK A/S (DK) 2006-10-31 — — US disclosed
EP-1558572-A2 NOVEL COMPOUNDS AND THEIR USE AS PRAR-MODULATORS NOVO NORDISK A/S (DK) 2005-08-03 — — EP disclosed
US-20050070583-A1 Novel compounds, their preparation and use VTVX HOLDINGS II LLC 2005-03-31 — — US disclosed
WO-2004037776-A2 NOVEL COMPOUNDS AND THEIR USE AS PRAR-MODULATORS NOVO NORDISK A/S (DK) 2004-05-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050070583-A1 Novel compounds, their preparation and use PPARG, PPARD, PPARA PPARD 2/4885PPARA 3/4885FFAR1 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.