⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13089679 | 1.00 | — | — | |
| SCHEMBL14963186 | 1.00 | — | — | |
| SCHEMBL29034898 | 1.00 | — | — | |
| SCHEMBL12986445 | 1.00 | — | — | |
| SCHEMBL327613 | 1.00 | — | — | |
| SCHEMBL12985951 | 1.00 | — | — | |
| SCHEMBL12985560 | 1.00 | — | — | |
| SCHEMBL21019458 | 0.95 | SLC1A2 (0.50) | — | |
| SCHEMBL12763445 | 0.90 | SLC1A2 (0.48) | — | |
| SCHEMBL25388011 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11732005-B2 | Peptidomimetic proteasome inhibitors | CORNELL UNIVERSITY (US) | 2023-08-22 | — | — | US | disclosed |
| CN-111819173-B | CD73 inhibitors | 伊莱利利公司 | 2023-06-06 | — | — | CN | disclosed |
| WO-2023014908-A1 | LPAR1 ANTAGONISTS AND USES THEREOF | Pipeline Therapeutics, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |
| US-20220056073-A1 | PEPTIDOMIMETIC PROTEASOME INHIBITORS | UNIV CORNELL (US) | 2022-02-24 | — | — | US | disclosed |
| US-11203613-B2 | Peptidomimetic proteasome inhibitors | CORNELL UNIVERSITY | 2021-12-21 | — | — | US | disclosed |
| US-10968203-B2 | Pyrimidinyl-pyridyloxy-naphthyl compounds and methods of treating IRE1-related diseases and disorders | GENENTECH, INC. (US) | 2021-04-06 | — | — | US | disclosed |
| US-20200317729-A1 | PEPTIDOMIMETIC PROTEASOME INHIBITORS | CORNELL UNIVERSITY | 2020-10-08 | — | — | US | disclosed |
| EP-3694605-A1 | PEPTIDOMIMETIC PROTEASOME INHIBITORS | Cornell University (US) | 2020-08-19 | — | — | EP | disclosed |
| CN-111247136-A | Pyrimidinyl-pyridyloxy-naphthyl compounds and methods of treating diseases and disorders associated with IRE1 | 吉宁特有限公司 | 2020-06-05 | — | — | CN | disclosed |
| CN-106502052-B | Etching-resistant phenolic aldehyde positive photoresist | 潍坊星泰克微电子材料有限公司 | 2020-01-14 | — | — | CN | disclosed |
| US-7247725-B2 | Gamma-aminoamide modulators of chemokine receptor activity | MERCK & CO., INC. (US) | 2007-07-24 | — | — | US | disclosed |
| US-7247725-B2 | Gamma-aminoamide modulators of chemokine receptor activity | MERCK & CO., INC. (US) | 2007-07-24 | — | — | US | disclosed |
| WO-2007011833-A2 | SPIROPIPERIDINE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | MERCK & CO., INC. (US) | 2007-01-25 | — | — | WO | disclosed |
| US-20070021454-A1 | Spiropiperidine beta-secretase inhibitors for the treatment of Alzheimer's disease | MERCK SHARP & DOHME LLC | 2007-01-25 | — | — | US | disclosed |
| US-20070021454-A1 | Spiropiperidine beta-secretase inhibitors for the treatment of Alzheimer's disease | MERCK SHARP & DOHME LLC | 2007-01-25 | — | — | US | disclosed |
| US-20070015771-A1 | Lonidamine analogs | THRESHOLD PHARMACEUTICALS, INC. (US) | 2007-01-18 | — | — | US | disclosed |
| CN-1277796-C | Process for the preparation of enantiomerically pure pyrethroid insecticides | SYNGENTA LTD (GB) | 2006-10-04 | — | — | CN | disclosed |
| EP-1592661-A2 | CYCLOPROPYL BETA-AMINO ACID DERIVATIVES | Warner-Lambert Company LLC (US) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004065361-A2 | CYCLOPROPYL BETA-AMINO ACID DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2004-08-05 | — | — | WO | disclosed |
| CN-1443153-A | Process for preparation of enantiomerically pure pyrethroid insecticides | SYNGENTA LTD (GB) | 2003-09-17 | — | — | CN | disclosed |