Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14460892 | 0.92 | HPGD (0.49) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL20411991 | 0.90 | HPGD (0.50) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL13968506 | 0.81 | KDM4E (0.64) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL20411990 | 0.81 | HPGD (0.47) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL13564039 | 0.81 | PSEN1 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5522131 | 0.80 | PSEN1 (0.45) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL13464722 | 0.77 | CYP1A2 (0.47) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL22373336 | 0.77 | HPGD (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL25752332 | 0.76 | ATM (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL18354306 | 0.75 | HPGD (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8134143-B2 | 2,7-carbazolenevinylene derivatives as novel materials in producing organic based electronic devices | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2012-03-13 | — | — | US | disclosed |