Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 10/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7200033 | 0.90 | GNRHR (0.52) | GNRHR | |
| SCHEMBL8600629 | 0.79 | GNRHR (1.00) | GNRHR | |
| Hydrochloric Acid SCHEMBL8698543 | 0.78 | GNRHR (0.98) | GNRHR | |
| SCHEMBL8695324 | 0.70 | GNRHR (0.50) | GNRHR | |
| Hydrochloric Acid SCHEMBL8694733 | 0.69 | GNRHR (0.49) | GNRHR | |
| SCHEMBL8600810 | 0.68 | GNRHR (0.81) | GNRHR | |
| SCHEMBL6974460 | 0.67 | GNRHR (0.79) | GNRHR | |
| SCHEMBL8690502 | 0.66 | GNRHR (0.76) | GNRHR | |
| SCHEMBL8695327 | 0.66 | NPY5R (0.45) | GNRHR | |
| SCHEMBL8695273 | 0.65 | GNRHR (1.00) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144605-A1 | RESCUE OF GONADOTROPIN RELEASING HORMONE RECEPTOR MUTANTS | OREGON HEALTH AND SCIENCE UNIVERSITY | 2010-06-10 | — | — | US | disclosed |
| US-7695917-B2 | Rescue of gonadotropin releasing hormone receptor mutants | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2010-04-13 | — | — | US | disclosed |
| US-20040191251-A1 | Rescue of gonadotropin releasing hormone receptor mutants | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-09-30 | — | — | US | disclosed |