SCHEMBL3277733

SCHEMBL3277733

C1=CC2(C1)CCC2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11775916 0.93
SCHEMBL6534020 0.90
SCHEMBL11773086 0.90
SCHEMBL11773606 0.90
SCHEMBL4527065 0.76
SCHEMBL21369994 0.74
SCHEMBL8055972 0.73
SCHEMBL135066 0.69
SCHEMBL22396413 0.67 MEN1 (0.38)
SCHEMBL19122440 0.67 CHRM2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4228758-B1 SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS AND THEIR DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF SANOFI SA (FR) 2024-07-24 EP claimed
WO-2024140638-A1 COMPOUND BASED ON SULFUR/OXYGEN SUBSTITUTED GLUTARIMIDE-BASED ISOINDOLINONE SKELETON AND USE THEREOF 标新生物医药科技(上海)有限公司 2024-07-04 WO claimed
WO-2024140637-A1 OXOISOINDOLINYL SUBSTITUTED PIPERIDINEDIONE DERIVATIVE AND USE THEREOF 标新生物医药科技(上海)有限公司 2024-07-04 WO claimed
CN-116615413-A Substituted 6, 7-dihydro-5H-benzo [7] rotaline compounds and derivatives thereof, method for the production and therapeutic use thereof 赛诺菲 2023-08-18 CN claimed
WO-2023151635-A1 COMPOUND BASED ON QUINAZOLINE-SUBSTITUTED GLUTARIMIDE SKELETON AND USE THEREOF 标新生物医药科技(上海)有限公司 2023-08-17 WO claimed
EP-3642264-A1 CURABLE SILICONE COMPOSITION AND APPLICATIONS AND USES THEREOF Momentive Performance Materials Inc. (US) 2020-04-29 EP claimed
US-10385210-B2 Curable silicone composition and applications and uses thereof MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2019-08-20 US claimed
US-10287400-B2 Curable silicone composition and applications and uses thereof MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2019-05-14 US claimed
EP-3443027-A1 CURABLE SILICONE COMPOSITION AND APPLICATIONS AND USES THEREOF Momentive Performance Materials Inc. (US) 2019-02-20 EP claimed
WO-2018236679-A1 CURABLE SILICONE COMPOSITION AND APPLICATIONS AND USES THEREOF MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-12-27 WO claimed
US-20180362764-A1 CURABLE SILICONE COMPOSITION AND APPLICATIONS AND USES THEREOF MOMENTIVE PERFORMANCE MATERIALS INC. 2018-12-20 US claimed
US-20170298188-A1 CURABLE SILICONE COMPOSITION AND APPLICATIONS AND USES THEREOF MOMENTIVE PERFORMANCE MATERIALS INC. 2017-10-19 US claimed
WO-2017180329-A1 CURABLE SILICONE COMPOSITION AND APPLICATIONS AND USES THEREOF MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2017-10-19 WO claimed
US-12612360-B2 Substituted 6,7-dihydro-5H-benzo[7]annulene compounds and their derivatives, processes for their preparation and therapeutic uses thereof SANOFI (FR) 2026-04-28 US disclosed
US-20260098018-A1 BICYCLIC 1,4-DIAZEPANONES AND THERAPEUTIC USES THEREOF CYTOKINETICS INC (US) 2026-04-09 US disclosed
US-12595230-B2 Substituted 6,7-dihydro-5H-benzo[7]annulene compounds and their derivatives, processes for their preparation and therapeutic uses thereof SANOFI (FR) 2026-04-07 US disclosed
US-20040167155-A1 Substituted dihydrophenanthridinesulfonamides WYETH 2004-08-26 US disclosed
WO-2004060894-A1 PYRROLO`2,1-C!`1,4! BENZODIAZEPINES AS VASOPRESSIN AGONISTS WYETH (US) 2004-07-22 WO disclosed
WO-2004050631-A1 SUBSTITUTED DIHYDROPHENANTHRIDINESUL FONAMIDES WYETH (US) 2004-06-17 WO disclosed
US-20030134845-A1 Biologically active vasopressin agonist metabolites WYETH (US) 2003-07-17 US disclosed