⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16236655 | 0.67 | — | — | |
| SCHEMBL11070095 | 0.67 | — | — | |
| SCHEMBL1071958 | 0.63 | — | — | |
| SCHEMBL10964764 | 0.63 | — | — | |
| SCHEMBL6492325 | 0.63 | — | — | |
| SCHEMBL9161853 | 0.61 | — | — | |
| SCHEMBL6018357 | 0.59 | — | — | |
| SCHEMBL19384216 | 0.59 | — | — | |
| SCHEMBL6406063 | 0.59 | — | — | |
| SCHEMBL8724662 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3215496-B1 | PANTOTHENAMIDE ANALOGUES | RADBOUD UNIV MEDISCH CENTRUM (NL) | 2019-01-02 | — | — | EP | disclosed |
| US-20180282279-A1 | Pantothenamide Analogues | TROPIQ HEALTH SCIENCES B.V. (NL) | 2018-10-04 | — | — | US | disclosed |
| EP-3215496-A2 | PANTOTHENAMIDE ANALOGUES | Radboud Universitair Medisch Centrum (NL) | 2017-09-13 | — | — | EP | disclosed |
| WO-2016072854-A2 | PANTOTHENAMIDE ANALOGUES | RADBOUD UNIVERSITAIR MEDISCH CENTRUM (NL) | 2016-05-12 | — | — | WO | disclosed |
| US-20140017797-A1 | PROTEIN AFFINITY TAG AND USES THEREOF | De Staadt der Nederlanden, vert doorde minister van VWS (NL) | 2014-01-16 | — | — | US | disclosed |
| EP-2651961-A1 | PROTEIN AFFINITY TAG AND USES THEREOF | De Staat Der Nederlanden, Vert. Door De Minister Van VWS (NL) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012081978-A1 | PROTEIN AFFINITY TAG AND USES THEREOF | DE STAAT DER NEDERLANDEN, VERT. DOOR DE MINISTER VAN VWS (NL) | 2012-06-21 | — | — | WO | disclosed |
| US-7700658-B2 | (R)-chiral halogenated substituted fused heterocyclic amino compounds useful for inhibiting cholesterol ester transfer protein activity | PFIZER INC. (US) | 2010-04-20 | — | — | US | disclosed |
| US-20090156685-A1 | (R)-CHIRAL HALOGENATED SUBSTITUTED FUSED HETEROCYCLIC AMINO COMPOUNDS USEFUL FOR INHIBITING CHOLESTEROL ESTER TRANSFER PROTEIN ACTIVITY | PFIZER INC | 2009-06-18 | — | — | US | disclosed |
| EP-2015751-A2 | SALTS OF PYRIDAZINE COMPOUNDS | Northwestern University (US) | 2009-01-21 | — | — | EP | disclosed |
| WO-2007127448-A2 | SALTS OF PYRIDAZINE COMPOUNDS | NORTHWESTERN UNIVERSITY (US) | 2007-11-08 | — | — | WO | disclosed |
| US-20070219274-A1 | (R)-Chiral Halogenated Substituted Fused Heterocyclic Amino Compounds Useful for Inhibiting Cholesterol Ester Transfer Protein Activity | PFIZER INC | 2007-09-20 | — | — | US | disclosed |
| US-20050165021-A1 | Polycyclic aryl and heteroaryl substituted 4-pyrones useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION (US) | 2005-07-28 | — | — | US | disclosed |
| US-20050054643-A1 | Substituted polycyclic aryl and heteroaryl pyrimidinones useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2005-03-10 | — | — | US | disclosed |
| WO-2004045509-A2 | METHOD OF USING A COX-2 INHIBITOR AND A 5-HT1A RECEPTOR MODULATOR AS A COMBINATION THERAPY | PHARMACIA CORPORATION (US) | 2004-06-03 | — | — | WO | disclosed |
| US-20030236257-A1 | Polycyclic aryl and heteroaryl substituted 4-pyridones useful for selective inhibition of the cogulation cascade | PHARMACIA CORPORATION | 2003-12-25 | — | — | US | disclosed |
| US-20030125328-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. (US) | 2003-07-03 | — | — | US | disclosed |
| US-20030050317-A1 | (R)-chiral halogenated substituted n,n-bis-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | SIKORSKI JAMES A (US) | 2003-03-13 | — | — | US | disclosed |