Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA known ✓ | P35790 | 1/20 | 0.48 |
| ▸ | ACHE known ✓ | P22303 | 7/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 7/20 | 0.39 |
| ▸ | CHAT | P28329 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1826398 | 0.97 | HTT (0.52) | HTTCHKABCHEACHECHAT | |
| Hydrochloric Acid SCHEMBL9358691 | 0.95 | HTT (0.50) | HTTCHKABCHEACHECHAT | |
| Iodide SCHEMBL7031853 | 0.95 | HTT (0.50) | HTTCHKABCHEACHECHAT | |
| Bromide SCHEMBL6416561 | 0.86 | HTT (0.57) | HTTCHKABCHEACHE | |
| Bromide SCHEMBL6433325 | 0.82 | HTT (0.64) | HTTCHKABCHEACHEMEN1 | |
| Bromide SCHEMBL14777821 | 0.82 | HTT (0.64) | HTTCHKABCHEACHEMEN1 | |
| Hydrochloric Acid SCHEMBL18986617 | 0.81 | HTT (0.57) | HTTCHKABCHEACHEMEN1 | |
| SCHEMBL21290572 | 0.81 | HTT (0.61) | HTTCHKABCHEACHEMEN1 | |
| Bromide SCHEMBL16339212 | 0.79 | CHKA (0.45) | HTTCHKABCHEACHECHAT | |
| Hydrochloric Acid SCHEMBL14778511 | 0.78 | HTT (0.64) | HTTCHKABCHEACHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12433962-B2 | Probes for imaging b-amyloid and inhibition of β-amyloid aggregation | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2025-10-07 | — | — | US | disclosed |
| CN-116063295-A | Probes for imaging and inhibiting beta-amyloid aggregation | 香港科技大学 | 2023-05-05 | — | — | CN | disclosed |
| US-20230133226-A1 | PROBES FOR IMAGING B-AMYLOID AND INHIBITION OF B-AMYLOID AGGREGATION | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2023-05-04 | — | — | US | disclosed |
| US-7700780-B2 | Zwitterionic chromophores and macromolecules containing such chromophores | Wang, Zhi Yuan (CA) | 2010-04-20 | — | — | US | disclosed |
| US-20060199951-A1 | Zwitterionic chromophores and macromolecules containing such chromophores | WANG ZHI Y | 2006-09-07 | — | — | US | disclosed |
| US-6894169-B1 | Zwitterionic chromophores and polymers containing such chromophores | NORTEL NETWORKS LIMITED (CA) | 2005-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133226-A1 | PROBES FOR IMAGING B-AMYLOID AND INHIBITION OF B-AMYLOID AGGREGATION | IAPP, APP, APBA1 | CHKA 3077/4885ACHE 458/4885HTT 38/4885 |
| US-12433962-B2 | Probes for imaging b-amyloid and inhibition of β-amyloid aggregation | IAPP, APP, APBA1 | CHKA 2813/4885ACHE 261/4885HTT 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.