Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tetrylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.53 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrylammonium SCHEMBL168440 | 0.97 | TSHR (0.57) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Tetrylammonium SCHEMBL18144308 | 0.93 | TSHR (0.53) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Tetrylammonium SCHEMBL8030879 | 0.90 | TSHR (0.50) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Tetrylammonium SCHEMBL9146986 | 0.90 | TSHR (0.50) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Tetrylammonium SCHEMBL30349943 | 0.87 | CA1 (0.53) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Tetrylammonium SCHEMBL49874 | 0.87 | CA1 (0.53) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Tetrylammonium SCHEMBL168442 | 0.87 | TSHR (0.53) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Tetrylammonium SCHEMBL36800 | 0.87 | TSHR (0.53) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Tetrylammonium SCHEMBL8538098 | 0.85 | CA4 (0.56) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Tetrylammonium SCHEMBL3361488 | 0.84 | CA1 (0.50) | TSHRNFKB1KCNA1KDM4EPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210140096-A1 | GRAPHENE MATERIAL COATING AND PREPARATION METHOD THEREOF, AIR FILTRATION DEVICE AND SYSTEM | HUBEI HIGHLAND GRAPHENE TECHNOLOGY CO., LTD. (CN) | 2021-05-13 | — | — | US | claimed |
| US-5693599-A | Flux washing agent | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1997-12-02 | — | — | US | claimed |
| EP-4039760-B1 | POLISHING COMPOSITION | FUJIMI INC (JP) | 2026-04-08 | — | — | EP | disclosed |
| EP-4717720-A1 | CATALYST COMPOSITION, BLOCKED POLYISOCYANATE COMPOSITION, COATING MATERIAL COMPOSITION, COATING FILM, AND METHOD FOR FORMING COATING FILM | Tosoh Corporation (JP) | 2026-04-01 | — | — | EP | disclosed |
| US-20250232831-A1 | METHOD FOR PREDICTING CELL MEMBRANE PERMEABILITY OF CYCLIC PEPTIDE | FUJIFILM CORPORATION (JP) | 2025-07-17 | — | — | US | disclosed |
| EP-4578866-A1 | METHOD FOR PREDICTING CELL MEMBRANE PERMEABILITY OF CYCLIC PEPTIDE | FUJIFILM Corporation (JP) | 2025-07-02 | — | — | EP | disclosed |
| WO-2024262553-A1 | CATALYST COMPOSITION, BLOCKED POLYISOCYANATE COMPOSITION, COATING MATERIAL COMPOSITION, COATING FILM, AND METHOD FOR FORMING COATING FILM | 東ソー株式会社 | 2024-12-26 | — | — | WO | disclosed |
| WO-2024202500-A1 | BLOCKED POLYISOCYANATE COMPOSITION, CURING AGENT FOR AQUEOUS COATING, AQUEOUS COATING COMPOSITION, AND COATING FILM | 東ソー株式会社 | 2024-10-03 | — | — | WO | disclosed |
| WO-2024043251-A1 | METHOD FOR PREDICTING CELL MEMBRANE PERMEABILITY OF CYCLIC PEPTIDE | 富士フイルム株式会社 | 2024-02-29 | — | — | WO | disclosed |
| EP-4039760-A1 | POLISHING COMPOSITION | Fujimi Incorporated (JP) | 2022-08-10 | — | — | EP | disclosed |
| CN-114450376-A | Polishing composition | 福吉米株式会社 | 2022-05-06 | — | — | CN | disclosed |
| EP-2105798-A1 | DEVELOPING SOLUTION AND METHOD FOR PRODUCTION OF FINELY PATTERNED MATERIAL | Sony Corporation (JP) | 2009-09-30 | — | — | EP | disclosed |
| EP-1334084-A4 | PHOSGENE-FREE PROCESS FOR PREPARING CARBAMATES | PHARMACIA & UPJOHN CO LLC (US) | 2005-11-02 | — | — | EP | disclosed |
| EP-1334084-A2 | PHOSGENE-FREE PROCESS FOR PREPARING CARBAMATES | PHARMACIA & UPJOHN COMPANY (US) | 2003-08-13 | — | — | EP | disclosed |
| US-6528678-B2 | Reacting an amine, such as 1-phenylpiperazine, with an alkylating agent, such as benzyl chloride, in the presence of carbon dioxide and cesium carbonate. | PHARMACIA& UPJOHN COMPANY | 2003-03-04 | — | — | US | disclosed |
| US-20020120140-A1 | Phosgene-free process for preparing carbamates | PHARMACIA & UPJOHN COMPANY | 2002-08-29 | — | — | US | disclosed |
| WO-2002034698-A2 | PHOSGENE-FREE PROCESS FOR PREPARING CARBAMATES | PHARMACIA & UPJOHN COMPANY (US) | 2002-05-02 | — | — | WO | disclosed |
| US-5693599-A | Flux washing agent | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1997-12-02 | — | — | US | disclosed |
| US-5516928-A | REACTION OF ISOPHORONE AND HYDROGEN CYANIDE USING QUATERNARY AMMONIUM CATALYST | BASF AKTIENGESELLSCHAFT (DE) | 1996-05-14 | — | — | US | disclosed |
| EP-0269949-A2 | Process for producing a high purity quaternary ammonium hydroxide | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1988-06-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020120140-A1 | Phosgene-free process for preparing carbamates | CPS1, MGMT, ALPG | TSHR 3219/4885NFKB1 4000/4885KCNA1 3276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.