Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.80 |
| ▸ | LMNA | P02545 | 1/20 | 0.80 |
| ▸ | MAPK10 | P53779 | 6/20 | 0.77 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.74 |
| ▸ | NPC1 | O15118 | 5/20 | 0.72 |
| ▸ | HPGD | P15428 | 4/20 | 0.71 |
| ▸ | RAB9A | P51151 | 4/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.71 |
| ▸ | THRB | P10828 | 1/20 | 0.71 |
| ▸ | FLT3 | P36888 | 1/20 | 0.66 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15281390 | 0.88 | MAPK10 (0.77) | MEN1KMT2AALDH1A1LMNAMAPK10 | |
| SCHEMBL23200418 | 0.87 | MAPK10 (0.76) | MEN1KMT2AALDH1A1LMNAMAPK10 | |
| SCHEMBL3277942 | 0.87 | MAPK10 (0.76) | MEN1KMT2AALDH1A1LMNAMAPK10 | |
| Gw572738X SCHEMBL3284953 | 0.87 | MAPK10 (1.00) | MEN1KMT2AALDH1A1LMNAMAPK10 | |
| SCHEMBL3278507 | 0.87 | MAPK10 (1.00) | MEN1KMT2AALDH1A1LMNAMAPK10 | |
| SCHEMBL3284934 | 0.86 | KMT2A (0.96) | MEN1KMT2AALDH1A1LMNAMAPK10 | |
| Gw620972X SCHEMBL29404766 | 0.85 | MAPK10 (1.00) | MEN1KMT2AALDH1A1LMNAMAPK10 | |
| Gw620972X SCHEMBL157875 | 0.85 | MAPK10 (1.00) | MEN1KMT2AALDH1A1LMNAMAPK10 | |
| SCHEMBL23200287 | 0.85 | MAPK10 (0.72) | MEN1KMT2AALDH1A1LMNAMAPK10 | |
| SCHEMBL31074969 | 0.84 | MAPK10 (0.98) | MEN1KMT2AALDH1A1LMNAMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700615-B2 | Cell migration inhibiting compositions and methods and compositions for treating cancer | AVOLIX PHARMACEUTICALS, INC. (US) | 2010-04-20 | — | — | US | disclosed |
| EP-1576110-A4 | CELL MIGRATION INHIBITING COMPOSITIONS AND METHODS AND COMPOSITIONS FOR TREATING CANCER | AVOLIX PHARMACEUTICALS (US) | 2007-11-07 | — | — | EP | disclosed |
| US-20060128742-A1 | Cell migration inhibiting compositions and methods and compositions for treating cancer | AVOLIX PHARMACEUTICALS, INC. | 2006-06-15 | — | — | US | disclosed |
| US-7012100-B1 | Cell migration inhibiting compositions and methods and compositions for treating cancer | AVOLIX PHARMACEUTICALS, INC. (US) | 2006-03-14 | — | — | US | disclosed |
| EP-1576110-A2 | CELL MIGRATION INHIBITING COMPOSITIONS AND METHODS AND COMPOSITIONS FOR TREATING CANCER | Avolix Pharmaceuticals (US) | 2005-09-21 | — | — | EP | disclosed |
| WO-2003102153-A2 | CELL MIGRATION INHIBITING COMPOSITIONS AND METHODS AND COMPOSITIONS FOR TREATING CANCER | AVOLIX PHARMACEUTICALS (US) | 2003-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128742-A1 | Cell migration inhibiting compositions and methods and compositions for treating cancer | MKI67, DCX, NUDC | MEN1 1184/4885KMT2A 4115/4885ALDH1A1 1944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.