SCHEMBL3279786

SCHEMBL3279786

C=C(/C=C/c1ccccc1)C(N)=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.57
HDAC3 O15379 2/20 0.57
HDAC4 P56524 2/20 0.57
HDAC1 Q13547 2/20 0.57
HDAC2 Q92769 2/20 0.57
HDAC8 Q9BY41 2/20 0.57
HDAC6 Q9UBN7 2/20 0.57
PLIN1 O60240 2/20 0.57
LMNA P02545 2/20 0.57
RECQL P46063 2/20 0.57
PLIN5 Q00G26 2/20 0.57
ABHD5 Q8WTS1 2/20 0.57
ALDH1A1 P00352 2/20 0.57
F3 P13726 2/20 0.57
TNKS O95271 1/20 0.57
HCAR2 Q8TDS4 1/20 0.57
HDAC7 Q8WUI4 1/20 0.57
HDAC10 Q969S8 1/20 0.57
HDAC11 Q96DB2 1/20 0.57
TNKS2 Q9H2K2 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1629733 1.00 MAPT (0.57) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL15120 0.83 MAPT (0.61) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL376003 0.83 MAPT (0.61) MAPTHDAC3HDAC4HDAC1HDAC2
Ammonia Solution, Strong SCHEMBL5175448 0.82 MAPT (0.59) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL28287153 0.82 MAPT (0.59) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL16268784 0.82 MAPT (0.59) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL4856786 0.81 MAPT (0.56) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL12252392 0.81 MAPT (0.56) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL24119310 0.80 GLA (0.64) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL7936575 0.80 MAPT (0.57) MAPTHDAC3HDAC4HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070099816-A1 Hard Surface Cleaning Composition THE CLOROX COMPANY 2007-05-03 US claimed
US-7700540-B2 Hard surface cleaning composition THE CLOROX COMPANY (US) 2010-04-20 US disclosed
US-20070099816-A1 Hard Surface Cleaning Composition THE CLOROX COMPANY 2007-05-03 US disclosed