SCHEMBL3280828

SCHEMBL3280828

C=CC(COC(=O)C(=C)C)P(=O)(O)O

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.52
ALDH1A1 P00352 2/20 0.39
THRB P10828 1/20 0.37
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4609973 0.81 TSHR (0.46) TSHRALDH1A1THRBCYP2D6CYP2C9
SCHEMBL6414251 0.78 TSHR (0.59) TSHRALDH1A1THRBCYP2D6CYP2C9
SCHEMBL3281544 0.77 TSHR (0.49) TSHRALDH1A1THRB
SCHEMBL5052500 0.77 TSHR (0.62) TSHRALDH1A1THRBCYP2D6CYP2C9
SCHEMBL8601929 0.77 TSHR (0.57) TSHRALDH1A1THRBCYP2D6CYP2C9
SCHEMBL3278845 0.77 TSHR (0.52) TSHRALDH1A1THRB
SCHEMBL27400837 0.76 TSHR (0.61) TSHRALDH1A1THRB
SCHEMBL15032675 0.75 TSHR (0.55) TSHRALDH1A1THRB
SCHEMBL15249364 0.74 TSHR (0.64) TSHRALDH1A1THRB
SCHEMBL2168104 0.74 TSHR (0.59) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1799741-B1 RADIATION CURABLE POWDER COATING COMPOSITIONS CYTEC SURFACE SPECIALTIES SA (BE) 2012-08-15 EP disclosed
US-7695773-B2 Radiation curable powder coating compositions CYTEC SURFACE SPECIALTIES, S.A. (BE) 2010-04-13 US disclosed
US-20080206480-A1 Radiation Curable Powder Coating Compositions ALLNEX BELGIUM S.A. (BE) 2008-08-28 US disclosed
EP-1799741-A1 RADIATION CURABLE POWDER COATING COMPOSITIONS CYTEC SURFACE SPECIALTIES, S.A. (BE) 2007-06-27 EP disclosed
WO-2006037493-A1 RADIATION CURABLE POWDER COATING COMPOSITIONS CYTEC SURFACE SPECIALTIES, S.A. (BE) 2006-04-13 WO disclosed
EP-1645583-A1 Radiation curable powder coating compositions CYTEC SURFACE SPECIALTIES, S.A. (BE) 2006-04-12 EP disclosed