SCHEMBL328180

SCHEMBL328180

O=C(O)C(=O)CCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6000096 0.96
SCHEMBL298779 0.79
SCHEMBL18670506 0.74 HAO1 (0.43)
SCHEMBL4957348 0.72 TSHR (0.47)
Oxalic Acid SCHEMBL27461073 0.72 TSHR (0.83)
SCHEMBL9651203 0.72 TSHR (0.40)
SCHEMBL9651208 0.72 TSHR (0.40)
SCHEMBL10507701 0.72 TSHR (0.40)
SCHEMBL6690358 0.72
Chloroacetic Acid SCHEMBL1330914 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 272 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117720674-B Modified chitosan, preparation method thereof, retarding water reducer and application 科之杰新材料集团有限公司 2026-05-19 CN claimed
WO-2024255217-A1 MODIFIED CHITOSAN AND PREPARATION METHOD THEREFOR, AND RETARDATION-TYPE WATER-REDUCING AGENT AND USE THEREOF 科之杰新材料集团有限公司 2024-12-19 WO claimed
CN-117720674-A Modified chitosan, preparation method thereof, retarding water reducer and application 科之杰新材料集团有限公司 2024-03-19 CN claimed
US-11077078-B2 Compositions and methods for the treatment of cancer KODISCOVERY, LLC (US) 2021-08-03 US claimed
US-10500175-B2 Compositions and methods for the treatment of cancer KODISCOVERY, LLC (US) 2019-12-10 US claimed
US-20190142775-A1 TREATING ACTIVATED DERMAL CONDITIONS WITH AGENTS THAT TARGET ENERGY METABOLISM SCIADERM, INC. 2019-05-16 US claimed
EP-2063881-B1 A COMPOSITION AND METHOD FOR THE EFFICACIOUS AND SAFE ADMINISTRATION OF HALOPYRUVATE FOR THE TREATMENT OF CANCER KO YOUNG HEE (US) 2019-05-08 EP claimed
EP-3452171-A1 TREATING ACTIVATED DERMAL CONDITIONS WITH AGENTS THAT TARGET ENERGY METABOLISM Sciaderm, Inc. (US) 2019-03-13 EP claimed
US-20180311192-A1 Compositions and Methods for the Treatment of Cancer KODISCOVERY, LLC 2018-11-01 US claimed
WO-2017192504-A1 TREATING ACTIVATED DERMAL CONDITIONS WITH AGENTS THAT TARGET ENERGY METABOLISM SCIADERM, INC. (US) 2017-11-09 WO claimed
US-20070292478-A1 Medical Implant Provided with Inhibitors of Atp Synthesis INTERSTITIAL THERAPEUTICS (CH) 2007-12-20 US claimed
WO-2007097989-A2 A COMPOSITION AND METHOD FOR THE EFFICACIOUS AND SAFE ADMINISTRATION OF HALOPYRUVATE FOR THE TREATMENT OF CANCER KO YOUNG HEE (US) 2007-08-30 WO claimed
US-20070203074-A1 Composition and method for the efficacious and safe administration of halopyruvate for the treatment of cancer KODISCOVERY, LLC 2007-08-30 US claimed
EP-1789030-A2 MEDICAL IMPLANT PROVIDED WITH INHIBITORS OF ATP SYNTHESIS Interstitial Therapeutics (CH) 2007-05-30 EP claimed
EP-1789107-A2 MEDICAL STENT PROVIDED WITH INHIBITORS OF ATP SYNTHESIS Interstitial Therapeutics (CH) 2007-05-30 EP claimed
WO-2006024488-A2 MEDICAL STENT PROVIDED WITH INHIBITORS OF ATP SYNTHESIS INTERSTITIAL THERAPEUTICS (CH) 2006-03-09 WO claimed
WO-2006024492-A2 MEDICAL IMPLANT PROVIDED WITH INHIBITORS OF ATP SYNTHESIS INTERSTITIAL THERAPEUTICS (CH) 2006-03-09 WO claimed
US-20030087961-A1 Therapeutics for cancer using 3-bromopyruvate and other selective inhibitors of ATP production NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-05-08 US claimed
EP-0994094-A1 Process for manufacturing 3-chloropyruvic acid Nippon Sanso Corporation (JP) 2000-04-19 EP claimed
US-4521534-A Imidazo[2,1-a]pyrrolo[2,1-c][1,4]benzodiazepine derivatives, methods of preparation and use AYERST, MCKENNA & HARRISON, LTD. (CA) 1985-06-04 US claimed