⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL486022 | 0.75 | — | — | |
| SCHEMBL4801625 | 0.70 | — | — | |
| SCHEMBL4247194 | 0.69 | — | — | |
| SCHEMBL7863609 | 0.68 | — | — | |
| SCHEMBL1706714 | 0.68 | — | — | |
| SCHEMBL4806362 | 0.65 | — | — | |
| SCHEMBL4391911 | 0.63 | — | — | |
| SCHEMBL5196281 | 0.63 | — | — | |
| SCHEMBL14660639 | 0.63 | — | — | |
| SCHEMBL1141344 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166937-A1 | ANTIPROLIFERATIVE COMPOUNDS AND METHODS OF USE THEREOF | Celgene Corporation (US) | 2017-05-17 | — | — | EP | disclosed |
| WO-2016007848-A1 | ANTIPROLIFERATIVE COMPOUNDS AND METHODS OF USE THEREOF | CELGENE CORPORATION (US) | 2016-01-14 | — | — | WO | disclosed |
| US-7714018-B2 | Heterocyclic antiviral compounds | ROCHE PALO ALTO LLC (US) | 2010-05-11 | — | — | US | disclosed |
| US-20070117859-A1 | Heterocyclic antiviral compounds | ROCHE PALO ALTO LLC | 2007-05-24 | — | — | US | disclosed |
| US-7164019-B2 | Such as cyclopentanecarboxylic acid {(S)-1-phenyl-3-[5-(pyridine-3-carbonyl)-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl]-propyl}-amide; antagonists of chemokine receptors, useful for treating/preventing human immunodeficiency virus infection, AIDS or ARC | ROCHE PALO ALTO LLC (US) | 2007-01-16 | — | — | US | disclosed |
| US-20060014767-A1 | Heterocyclic antiviral compounds | ROCHE PALO ALTO LLC | 2006-01-19 | — | — | US | disclosed |
| EP-0257771-B1 | Herbicidal method using diflufenican | MAY & BAKER LTD (GB) | 1994-03-23 | — | — | EP | disclosed |
| EP-0274892-B1 | METHOD OF KILLING WEEDS COMPRISING THE USE OF DIFLUFENICAN | MAY & BAKER LIMITED (GB) | 1992-08-12 | — | — | EP | disclosed |
| EP-0273669-B1 | HERBICIDAL METHOD COMPRISING THE USE OF DIFLUFENICAN | MAY & BAKER LIMITED (GB) | 1992-07-01 | — | — | EP | disclosed |
| EP-0273668-B1 | HERBICIDAL METHOD USING DIFLUFENICAN | MAY & BAKER LIMITED (GB) | 1992-07-01 | — | — | EP | disclosed |
| EP-0290257-B1 | HERBICIDAL METHOD COMPRISING THE USE OF DIFLUFENICAN | MAY & BAKER LIMITED (GB) | 1992-04-15 | — | — | EP | disclosed |
| EP-0255272-B1 | HERBICIDAL METHOD COMPRISING THE USE OF DIFLUFENICAN | MAY & BAKER LIMITED (GB) | 1991-12-11 | — | — | EP | disclosed |
| EP-0290257-A2 | Herbicidal method comprising the use of diflufenican | MAY & BAKER LIMITED (GB) | 1988-11-09 | — | — | EP | disclosed |