Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16239227 | 1.00 | MAPT (0.47) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL16239206 | 1.00 | MAPT (0.47) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL16239066 | 1.00 | MAPT (0.47) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL16239698 | 1.00 | MAPT (0.47) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL16239099 | 1.00 | MAPT (0.47) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL16239693 | 1.00 | MAPT (0.47) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL16239274 | 1.00 | MAPT (0.47) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL16239291 | 1.00 | MAPT (0.47) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL15674708 | 1.00 | MAPT (0.47) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL16239662 | 1.00 | MAPT (0.47) | MAPTABCC4ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10118978-B2 | Vinyl alcohol polymer and production method thereof, additive for drilling mud, drilling mud, additive for drilling cement slurry, and drilling cement slurry | KURARAY CO., LTD. (JP) | 2018-11-06 | — | — | US | disclosed |
| US-9908961-B2 | Vinyl alcohol-based graft polymer, method for producing same, and ion-exchange membrane using same | KURARAY CO., LTD. (JP) | 2018-03-06 | — | — | US | disclosed |
| US-20180044491-A1 | ION-EXCHANGE MEMBRANE | KURARAY CO., LTD. (JP) | 2018-02-15 | — | — | US | disclosed |
| CN-107428969-A | ion exchange membrane | 株式会社可乐丽 | 2017-12-01 | — | — | CN | disclosed |
| US-9611344-B2 | Vinyl alcohol polymer, method for producing same, and composition and coating agent containing vinyl alcohol polymer | KURARAY CO., LTD. (JP) | 2017-04-04 | — | — | US | disclosed |
| EP-2803681-B1 | VINYL ALCOHOL POLYMER AND METHOD FOR PRODUCING SAME, AND COMPOSITION AND COATING AGENT CONTAINING VINYL ALCOHOL POLYMER | KURARAY CO (JP) | 2017-03-01 | — | — | EP | disclosed |
| US-20160229936-A1 | VINYL ALCOHOL POLYMER AND PRODUCTION METHOD THEREOF, ADDITIVE FOR DRILLING MUD, DRILLING MUD, ADDITIVE FOR DRILLING CEMENT SLURRY, AND DRILLING CEMENT SLURRY | KURARAY CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
| EP-3040350-A1 | NOVEL VINYL ALCOHOL BASED COPOLYMER, PRODUCTION METHOD FOR SAME, AND ION EXCHANGE MEMBRANE | Kuraray Co., Ltd. (JP) | 2016-07-06 | — | — | EP | disclosed |
| US-20160168346-A1 | NOVEL VINYL ALCOHOL BASED COPOLYMER, PRODUCTION METHOD FOR SAME, AND ION EXCHANGE MEMBRANE | KURARAY CO., LTD. (JP) | 2016-06-16 | — | — | US | disclosed |
| US-20150259457-A1 | VINYL ALCOHOL-BASED GRAFT POLYMER, METHOD FOR PRODUCING SAME, AND ION-EXCHANGE MEMBRANE USING SAME | KURARAY CO., LTD. (JP) | 2015-09-17 | — | — | US | disclosed |
| US-20140350169-A1 | VINYL ALCOHOL POLYMER, METHOD FOR PRODUCING SAME, AND COMPOSITION AND COATING AGENT CONTAINING VINYL ALCOHOL POLYMER | KURARAY CO., LTD. (JP) | 2014-11-27 | — | — | US | disclosed |
| EP-2803681-A1 | VINYL ALCOHOL POLYMER AND METHOD FOR PRODUCING SAME, AND COMPOSITION AND COATING AGENT CONTAINING VINYL ALCOHOL POLYMER | Kuraray Co., Ltd. (JP) | 2014-11-19 | — | — | EP | disclosed |
| US-7709494-B2 | for lowering blood glucose, treating diabetes, or increasing insulin release, hyperglycemia; (1S,3R)-3-(4,5-Diphenylpyrimidin-2-yloxymethyl)cyclohexanecarboxylic acid | SANOFI-AVENTIS (DE) | 2010-05-04 | — | — | US | disclosed |
| US-20090149486-A1 | 4,5-DIPHENYL-PYRIMIDINYL-OXY OR -MERCAPTO SUBSTITUTED CARBOXYLIC ACIDS, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | SANOFI-AVENTIS (FR) | 2009-06-11 | — | — | US | disclosed |
| CN-101421249-A | 4,5-diphenyl-pyrimidinyl-oxy or -mercapto substituted carboxylic acids, method for the production and use thereof as medicaments | SANOFI AVENTIS DEUTSCHLAND (FR) | 2009-04-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149486-A1 | 4,5-DIPHENYL-PYRIMIDINYL-OXY OR -MERCAPTO SUBSTITUTED CARBOXYLIC ACIDS, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | SLC5A1, SLC5A2, DPP4 | MAPT 3972/4885ABCC4 603/4885ALDH1A1 726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.