Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10289271 | 0.92 | SCN9A (0.72) | SCN9A | |
| SCHEMBL6466712 | 0.89 | SCN9A (0.83) | SCN9A | |
| SCHEMBL328251 | 0.88 | SCN9A (0.66) | SCN9A | |
| SCHEMBL328268 | 0.85 | SCN9A (0.61) | SCN9A | |
| SCHEMBL328160 | 0.84 | SCN9A (0.60) | SCN9A | |
| SCHEMBL10289199 | 0.83 | SCN9A (0.58) | SCN9A | |
| SCHEMBL10289026 | 0.81 | SCN9A (0.60) | SCN9A | |
| SCHEMBL10289495 | 0.80 | SCN9A (0.54) | SCN9A | |
| SCHEMBL10289188 | 0.80 | SCN9A (0.55) | SCN9A | |
| SCHEMBL281851 | 0.80 | SCN9A (0.94) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428515-A1 | Spiro-oxindole compounds and their uses as therapeutic agents | Xenon Pharmaceuticals Inc. (CA) | 2012-03-14 | — | — | EP | disclosed |