Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PABPC1 | P11940 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22773569 | 0.77 | KMT2A (0.65) | RAB9ANPC1KDM4EALDH1A1LMNA | |
| SCHEMBL9954855 | 0.77 | KMT2A (0.56) | RAB9ANPC1KDM4EALDH1A1LMNA | |
| SCHEMBL3761569 | 0.73 | KMT2A (0.68) | RAB9ANPC1KDM4EALDH1A1LMNA | |
| SCHEMBL50309 | 0.73 | KMT2A (0.67) | RAB9ANPC1KDM4EALDH1A1LMNA | |
| SCHEMBL31129249 | 0.73 | KMT2A (0.67) | RAB9ANPC1KDM4EALDH1A1LMNA | |
| SCHEMBL10404298 | 0.73 | KMT2A (0.67) | RAB9ANPC1KDM4EALDH1A1LMNA | |
| Nitric Acid SCHEMBL8140767 | 0.72 | KMT2A (0.59) | RAB9ANPC1KDM4EALDH1A1LMNA | |
| Nitric Acid SCHEMBL8140768 | 0.72 | KMT2A (0.59) | RAB9ANPC1KDM4EALDH1A1LMNA | |
| Nitric Acid SCHEMBL2086157 | 0.72 | KMT2A (0.59) | RAB9ANPC1KDM4EALDH1A1LMNA | |
| Nitric Acid SCHEMBL27824883 | 0.72 | KMT2A (0.59) | RAB9ANPC1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428508-A1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | Astellas Pharma Inc. (JP) | 2012-03-14 | — | — | EP | disclosed |