SCHEMBL3284522

SCHEMBL3284522

c1cnc2ccc(N=Nc3ccc4ncccc4c3)cc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.61
NPC1 O15118 4/20 0.61
MEN1 O00255 4/20 0.61
KMT2A Q03164 4/20 0.61
RAB9A P51151 3/20 0.61
ATM Q13315 3/20 0.61
MAPK1 P28482 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
POLB P06746 3/20 0.61
ALDH1A1 P00352 5/20 0.57
HTT P42858 3/20 0.57
KDM4E B2RXH2 3/20 0.57
TP53 P04637 2/20 0.57
HSP90AA1 P07900 1/20 0.57
HSP90AB1 P08238 1/20 0.57
TSHR P16473 1/20 0.57
CASP1 P29466 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
HSD17B10 Q99714 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19970705 0.87 MAPT (0.73) MAPTNPC1MEN1KMT2ARAB9A
SCHEMBL2682105 0.87 MAPT (0.73) MAPTNPC1MEN1KMT2ARAB9A
SCHEMBL18673663 0.86 NPC1 (0.59) MAPTNPC1MEN1KMT2ARAB9A
SCHEMBL25159368 0.84 NPC1 (0.57) MAPTNPC1MEN1KMT2ARAB9A
SCHEMBL16707057 0.84 NPC1 (0.57) MAPTNPC1MEN1KMT2ARAB9A
SCHEMBL11173067 0.83 NPC1 (0.52) MAPTNPC1MEN1KMT2ARAB9A
SCHEMBL8123245 0.83 NPC1 (0.52) MAPTNPC1MEN1KMT2ARAB9A
SCHEMBL28600805 0.81 MAPT (0.46) MAPTNPC1MEN1KMT2ARAB9A
SCHEMBL20378240 0.80 NPC1 (0.52) MAPTNPC1MEN1KMT2ARAB9A
SCHEMBL17626267 0.80 NPC1 (0.52) MAPTNPC1MEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021074275-A1 EFFECTIVE PHOTOMODULATION OF LANTHANIDE (III) ION LUMINESCENCE IN THE VISIBLE OR NEAR-INFRARED RANGE UNIVERSITE DE RENNES 1 (FR) 2021-04-22 WO disclosed
US-9868873-B2 Photochromic security enabled ink for digital offset printing applications XEROX CORPORATION (US) 2018-01-16 US disclosed
US-9404001-B2 Photochromic latex ink XEROX CORPORATION (US) 2016-08-02 US disclosed
US-20150153479-A1 PHOTOCHROMIC LATEX INK XEROX CORPORATION (US) 2015-06-04 US disclosed
US-20130305947-A1 PHOTOCHROMIC SECURITY ENABLED INK FOR DIGITAL OFFSET PRINTING APPLICATIONS XEROX CORPORATION (US) 2013-11-21 US disclosed
US-7708396-B2 Photochromic phase change inks XEROX CORPORATION (US) 2010-05-04 US disclosed
US-20070211124-A1 PHOTOCHROMIC PHASE CHANGE INKS XEROX CORPORATION (US) 2007-09-13 US disclosed
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 US disclosed
US-5710420-A Method for embedding and recovering machine-readable information XEROX CORPORATION (US) 1998-01-20 US disclosed
US-5633109-A Ink compositions with liposomes containing photochromic compounds XEROX CORPORATION (US) 1997-05-27 US disclosed
US-5593486-A Photochromic hot melt ink compositions XEROX CORPORATION (US) 1997-01-14 US disclosed
US-5551973-A LIQUID CRYSTAL GEL PHASE, MICROEMULSION PHASE XEROX CORPORATION (US) 1996-09-03 US disclosed