Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 10/20 | 0.51 |
| ▸ | MAPT | P10636 | 10/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.51 |
| ▸ | BLM | P54132 | 8/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 5/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.51 |
| ▸ | RECQL | P46063 | 4/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.51 |
| ▸ | APEX1 | P27695 | 3/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23040664 | 0.89 | KDM4E (0.53) | TDP1MAPTKDM4EBLMADRB2 | |
| SCHEMBL23040663 | 0.89 | KDM4E (0.53) | TDP1MAPTKDM4EBLMADRB2 | |
| SCHEMBL521780 | 0.82 | MAPT (0.58) | TDP1MAPTKDM4EBLMADRB2 | |
| SCHEMBL521779 | 0.82 | MAPT (0.58) | TDP1MAPTKDM4EBLMADRB2 | |
| SCHEMBL23318970 | 0.82 | MAPT (0.46) | TDP1MAPTKDM4EBLMADRB2 | |
| SCHEMBL11212431 | 0.81 | MAPT (0.44) | TDP1MAPTKDM4EBLMADRB2 | |
| SCHEMBL10878881 | 0.81 | MAPT (0.44) | TDP1MAPTKDM4EBLMADRB2 | |
| SCHEMBL17053665 | 0.81 | MAPT (0.56) | TDP1MAPTKDM4EBLMADRB2 | |
| SCHEMBL12238827 | 0.81 | TAAR1 (0.47) | TDP1MAPTKDM4EBLMMEN1 | |
| SCHEMBL29633156 | 0.81 | TAAR1 (0.47) | TDP1MAPTKDM4EBLMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8912332-B2 | Synthesis of trivalent flexible frameworks with ligands comprising catechol units for functionalizing surfaces | JUSTUS-LIEBIG-UNIVERSITAET GIESSEN (DE) | 2014-12-16 | — | — | US | disclosed |
| US-8912332-B2 | Synthesis of trivalent flexible frameworks with ligands comprising catechol units for functionalizing surfaces | JUSTUS-LIEBIG-UNIVERSITAET GIESSEN (DE) | 2014-12-16 | — | — | US | disclosed |
| EP-2428502-B1 | Synthesis of tripodal catechol derivatives with an adamantyl base for functionalising surfaces | Justus Liebig Universität Giessen (DE) | 2014-12-10 | — | — | EP | disclosed |
| EP-2428503-B1 | Synthesis of tripodal catechol derivatives with a flexible base for functionalising surfaces | Justus Liebig Universität Giessen (DE) | 2014-12-10 | — | — | EP | disclosed |
| US-8785641-B2 | Synthesis of tripodal catechol derivatives having an adamantyl basic framework for functionalizing surfaces | JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) | 2014-07-22 | — | — | US | disclosed |
| US-8785641-B2 | Synthesis of tripodal catechol derivatives having an adamantyl basic framework for functionalizing surfaces | JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) | 2014-07-22 | — | — | US | disclosed |
| US-20130245269-A1 | Synthesis of Tripodal Catechol Derivatives Having an Adamantyl Basic Framework for Functionalizing Surfaces | JUSTUS-LIEBIG-UNIVERSITA GIESSEN (DE) | 2013-09-19 | — | — | US | disclosed |
| US-20130245269-A1 | Synthesis of Tripodal Catechol Derivatives Having an Adamantyl Basic Framework for Functionalizing Surfaces | JUSTUS-LIEBIG-UNIVERSITA GIESSEN (DE) | 2013-09-19 | — | — | US | disclosed |
| US-20130245270-A1 | Synthesis of Trivalent Flexible Frameworks with Ligands Comprising Catechol Units for Functionalizing Surfaces | JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) | 2013-09-19 | — | — | US | disclosed |
| US-20130245270-A1 | Synthesis of Trivalent Flexible Frameworks with Ligands Comprising Catechol Units for Functionalizing Surfaces | JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) | 2013-09-19 | — | — | US | disclosed |
| WO-2012032084-A1 | SYNTHESIS OF TRIPODAL CATECHOL DERIVATIVES HAVING AN ADAMANTYL BASIC FRAMEWORK FOR FUNCTIONALIZING SURFACES | JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) | 2012-03-15 | — | — | WO | disclosed |
| WO-2012032085-A1 | SYNTHESIS OF TRIVALENT FLEXIBLE FRAMEWORKS WITH LIGANDS COMPRISING CATECHOL UNITS FOR FUNCTIONALIZING SURFACES | JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) | 2012-03-15 | — | — | WO | disclosed |
| EP-2428503-A1 | Synthesis of tripodal catechol derivatives with a flexible base for functionalising surfaces | Justus-Liebig-Universität Gießen (DE) | 2012-03-14 | — | — | EP | disclosed |
| EP-2428502-A1 | Synthesis of tripodal catechol derivatives with an adamantyl base for functionalising surfaces | Justus-Liebig-Universität Gießen (DE) | 2012-03-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130245270-A1 | Synthesis of Trivalent Flexible Frameworks with Ligands Comprising Catechol Units for Functionalizing Surfaces | CHRM3, CHRM5, CHRM4 | TDP1 4517/4885MAPT 4034/4885KDM4E 1565/4885 |
| US-20130245269-A1 | Synthesis of Tripodal Catechol Derivatives Having an Adamantyl Basic Framework for Functionalizing Surfaces | CHRM1, CHRM5, CHRM4 | TDP1 3262/4885MAPT 2680/4885KDM4E 2443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.