Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3286419 | 0.96 | SLC6A2 (0.63) | SLC6A2SLC6A4 | |
| SCHEMBL3286312 | 0.94 | SLC6A2 (0.51) | SLC6A2SLC6A4 | |
| SCHEMBL3286935 | 0.94 | SLC6A2 (0.62) | SLC6A2SLC6A4 | |
| SCHEMBL3287067 | 0.93 | SLC6A2 (0.67) | SLC6A2SLC6A4 | |
| SCHEMBL3292929 | 0.91 | SLC6A2 (0.48) | SLC6A2SLC6A4 | |
| SCHEMBL3288844 | 0.88 | SLC6A2 (0.56) | SLC6A2SLC6A4 | |
| SCHEMBL3288750 | 0.88 | SLC6A2 (0.53) | SLC6A2SLC6A4 | |
| SCHEMBL3286527 | 0.88 | SLC6A2 (0.72) | SLC6A2SLC6A4 | |
| SCHEMBL3294832 | 0.84 | SLC6A2 (0.56) | SLC6A2SLC6A4 | |
| SCHEMBL13325531 | 0.84 | SLC6A2 (0.71) | SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718652-B2 | Substituted benzothiadiazinedioxide derivatives and methods of their use | WYETH LLC (US) | 2010-05-18 | — | — | US | claimed |
| US-20080161295-A1 | SUBSTITUTED BENZOTHIADIAZINEDIOXIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-07-03 | — | — | US | claimed |
| US-7718652-B2 | Substituted benzothiadiazinedioxide derivatives and methods of their use | WYETH LLC (US) | 2010-05-18 | — | — | US | disclosed |
| US-20080161295-A1 | SUBSTITUTED BENZOTHIADIAZINEDIOXIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161295-A1 | SUBSTITUTED BENZOTHIADIAZINEDIOXIDE DERIVATIVES AND METHODS OF THEIR USE | SLC6A2, SLC6A4, DBH | SLC6A2 1/4885SLC6A4 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.