Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 10/20 | 0.53 |
| ▸ | DPP4 | P27487 | 3/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 7/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.41 |
| ▸ | ANPEP | P15144 | 3/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL993935 | 0.91 | MCL1 (0.44) | MCL1DPP4NR1H2NR1H3BCL2 | |
| SCHEMBL3289495 | 0.90 | MCL1 (0.44) | MCL1DPP4NR1H2NR1H3BCL2 | |
| SCHEMBL1518018 | 0.87 | DPP4 (0.42) | MCL1DPP4NR1H2NR1H3BCL2 | |
| SCHEMBL14003735 | 0.86 | MCL1 (0.40) | MCL1DPP4NR1H2NR1H3BCL2 | |
| SCHEMBL14003734 | 0.86 | MCL1 (0.40) | MCL1DPP4NR1H2NR1H3BCL2 | |
| SCHEMBL14003739 | 0.84 | ANPEP (0.45) | MCL1DPP4NR1H2NR1H3BCL2 | |
| SCHEMBL3284746 | 0.84 | MCL1 (0.52) | MCL1DPP4NR1H2NR1H3BCL2 | |
| SCHEMBL6512039 | 0.84 | ANPEP (0.41) | MCL1DPP4NR1H2NR1H3BCL2 | |
| SCHEMBL3285110 | 0.84 | MCL1 (0.56) | MCL1NR1H3BCL2PRMT1LMNA | |
| SCHEMBL14003757 | 0.83 | ANPEP (0.56) | MCL1DPP4NR1H2NR1H3BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7714044-B2 | Use of 4-cyano-naphthalene-1, 8-dicarboximide derivatives and related compounds to protect organic material from the damaging effects of light | BASF AKITENGESELLSCHAFT (DE) | 2010-05-11 | — | — | US | disclosed |
| EP-1687278-B1 | USE OF 4-CYANO-NAPHTHALENE-1, 8-DICARBOXIMIDE DERIVATIVES AND RELATED COMPOUNDS TO PROTECT ORGANIC MATERIAL FROM THE DAMAGING EFFECTS OF LIGHT | BASF SE (DE) | 2009-03-11 | — | — | EP | disclosed |
| US-20070100033-A1 | Use of 4-cyano-naphthalene-1, 8-dicarboximide derivatives and related compounds to protect organic material from the damaging effects of light | BAST AKTIENGESELLSCHAFT (DE) | 2007-05-03 | — | — | US | disclosed |