Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | FDPS | P14324 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19405762 | 1.00 | TSHR (0.57) | TSHRFDPSPOLBAPEX1HTT | |
| SCHEMBL19409701 | 1.00 | TSHR (0.57) | TSHRFDPSPOLBAPEX1HTT | |
| SCHEMBL1262620 | 0.84 | TSHR (0.54) | TSHRFDPSPOLBAPEX1HTT | |
| SCHEMBL1263022 | 0.84 | TSHR (0.54) | TSHRFDPSPOLBAPEX1HTT | |
| SCHEMBL5053937 | 0.84 | TSHR (0.53) | TSHRFDPSPOLBAPEX1HTT | |
| SCHEMBL19405753 | 0.82 | TSHR (0.51) | TSHRFDPSPOLBAPEX1HTT | |
| SCHEMBL19405710 | 0.82 | TSHR (0.51) | TSHRFDPSPOLBAPEX1HTT | |
| SCHEMBL15389725 | 0.81 | TSHR (0.62) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL12504625 | 0.81 | TSHR (0.62) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL2943884 | 0.81 | TSHR (0.62) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404144-B2 | Compositions including polymerizable bisphosphonic acids and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-03-26 | — | — | US | disclosed |
| EP-2407142-A1 | Use of polymerizable bisphosphonic acids for the treatment of tooth surfaces that are not pretreated with phosphoric acid | 3M Innovative Properties Company (US) | 2012-01-18 | — | — | EP | disclosed |
| US-20090075239-A1 | COMPOSITIONS INCLUDING POLYMERIZABLE BISPHOSPHONIC ACIDS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY | 2009-03-19 | — | — | US | disclosed |
| EP-1578377-A1 | COMPOSITIONS INCLUDING POLYMERIZABLE BISPHOSPHONIC ACIDS AND METHODS | 3M Innovative Properties Company (US) | 2005-09-28 | — | — | EP | disclosed |
| US-20040206932-A1 | Compositions including polymerizable bisphosphonic acids and methods | 3M INNOVATIVE PROPERTIES COMPANY | 2004-10-21 | — | — | US | disclosed |
| WO-2004060327-A1 | COMPOSITIONS INCLUDING POLYMERIZABLE BISPHOSPHONIC ACIDS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2004-07-22 | — | — | WO | disclosed |