Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CLTC | Q00610 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1009329 | 0.83 | HSD17B10 (0.52) | ALDH1A1HSD17B10PARP1TDP1PRKCI | |
| Benzene SCHEMBL29261851 | 0.68 | GAA (0.56) | ALDH1A1TDP1HPGDKDM4EMAPK1 | |
| SCHEMBL16034285 | 0.68 | GAA (0.62) | ALDH1A1HSD17B10TDP1HPGDKDM4E | |
| SCHEMBL10663598 | 0.68 | GAA (0.62) | ALDH1A1HSD17B10TDP1HPGDKDM4E | |
| SCHEMBL57154 | 0.68 | GAA (0.62) | ALDH1A1HSD17B10TDP1HPGDKDM4E | |
| SCHEMBL10917087 | 0.68 | GAA (0.62) | ALDH1A1HSD17B10TDP1HPGDKDM4E | |
| SCHEMBL14914636 | 0.68 | PARP1 (0.52) | ALDH1A1HSD17B10PARP1TDP1PRKCI | |
| Water SCHEMBL8364047 | 0.66 | GAA (0.59) | ALDH1A1HSD17B10TDP1HPGDKDM4E | |
| SCHEMBL9506974 | 0.66 | GAA (0.59) | ALDH1A1HSD17B10TDP1HPGDKDM4E | |
| Water SCHEMBL27456421 | 0.66 | GAA (0.59) | ALDH1A1HSD17B10TDP1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7695898-B2 | Photothermographic material and image formation method | FUJIFILM CORPORATION (JP) | 2010-04-13 | — | — | US | disclosed |
| US-20090123881-A1 | PHOTOTHERMOGRAPHIC MATERIAL AND IMAGE FORMATION METHOD | FUJIFILM CORPORATION (JP) | 2009-05-14 | — | — | US | disclosed |
| US-6699653-B2 | Photographic films containing group IB compounds such as silver behenate or stearate, silver halides and reducing agents on radiation transparent supports, having storage stability; antifogging | FUJI PHOTO FILM CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| US-20030165784-A1 | Photographic films containing group IB compounds such as silver behenate or stearate, silver halides and reducing agents on radiation transparent supports, having storage stability; antifogging | FUJIFILM CORPORATION (JP) | 2003-09-04 | — | — | US | disclosed |
| US-20030118954-A1 | Photothermographic material and image formation method | FUJIFILM CORPORATION (JP) | 2003-06-26 | — | — | US | disclosed |
| US-5656419-A | CONTAINING COMPOUND HAVING OXIDIZED NITROGEN-CONTAINING HETEROCYCLIC GROUP; HIGH CONTRAST IMAGE | FUJI PHOTO FILM CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |