⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23741 | 0.95 | — | — | |
| SCHEMBL11244260 | 0.95 | — | — | |
| Phosphine SCHEMBL28963125 | 0.90 | — | — | |
| Lithium SCHEMBL3205664 | 0.90 | TSHR (0.36) | — | |
| SCHEMBL10983922 | 0.90 | — | — | |
| Fluoride SCHEMBL28001662 | 0.90 | — | — | |
| SCHEMBL29550687 | 0.76 | — | — | |
| Bicarbonate SCHEMBL7827761 | 0.76 | TP53 (0.39) | — | |
| SCHEMBL1960480 | 0.70 | — | — | |
| SCHEMBL835953 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020223672-A1 | FUNCTIONALIZED CYCLIC POLYMERS AND METHODS OF PREPARING SAME | UNIVERSITY OF FLORIDA RESEARCHFOUNDATION, INC. (US) | 2020-11-05 | — | — | WO | disclosed |
| EP-2903965-A1 | N-PROP-2-YNYL CARBOXAMIDE DERIVATIVES AND THEIR USE AS TRPA1 ANTAGONISTS | Orion Corporation (FI) | 2015-08-12 | — | — | EP | disclosed |
| WO-2014053694-A1 | N-PROP-2-YNYL CARBOXAMIDE DERIVATIVES AND THEIR USE AS TRPA1 ANTAGONISTS | ORION CORPORATION (FI) | 2014-04-10 | — | — | WO | disclosed |
| US-7714168-B2 | N-(1,1-diemthylpropyl)-4-(2-propynyloxy)-3-methoxybenzamide; N-(2,2-diemthylpropyl)-4-(2-propynyloxy)-3-methoxybenzamide; controlling plant diseases | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-05-11 | — | — | US | disclosed |
| EP-1940779-B1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL CO (JP) | 2009-07-22 | — | — | EP | disclosed |
| US-20080319080-A1 | Amide Compounds and Their Use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-12-25 | — | — | US | disclosed |
| EP-1497317-A2 | DIPEPTIDIC GROWTH HORMONE SECRETAGOGUES | ELI LILLY AND COMPANY (US) | 2005-01-19 | — | — | EP | disclosed |
| EP-1497316-A2 | GROWTH HORMONE SECRETAGOGUES | ELI LILLY AND COMPANY (US) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003087070-A2 | GROWTH HORMONE SECRETAGOGUES | ELI LILLY AND COMPANY (US) | 2003-10-23 | — | — | WO | disclosed |
| WO-2003087069-A2 | DIPEPTIDIC GROWTH HORMONE SECRETAGOGUES | ELI LILLY AND COMPANY (US) | 2003-10-23 | — | — | WO | disclosed |
| EP-0920310-A1 | USE OF AMINOTHIOLESTER DERIVATIVES IN PHARMACEUTICS | Galderma Research & Development, S.N.C. (FR) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998044919-A1 | USE OF AMINOTHIOLESTER DERIVATIVES IN PHARMACEUTICS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 1998-10-15 | — | — | WO | disclosed |